Patient P-01346
Synthetic patientNBL-101 · Day 106 · 55–64 · F · baseline S12Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
11%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S12
- Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 14 DT-01 recommended — Dosing / Timing Recommendation DT-01
- Day 15 Patient accepted — Started DT-01 in the companion
- Day 20 GI symptom burden −12% vs expected — Dosing / Timing Recommendation DT-01
- Day 26 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 12.
Primary contributors, last 14 days
- Toxicity+9
- Inflammatory activity+8
- GI instability-4
What helped?
- Dosing / Timing Recommendation DT-01Day 14Result: symptom burden −12%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion12.5/100
improving · -8.0 vs previous 14 d
Toxicity
Blood20.9/100
stable · +0.5 vs previous 14 d
Sleep quality
Wearable34/100
improving · +2.5 vs previous 14 d
Energy level
Daily log5.3/10
improving · +0.3 vs previous 14 d
Stress level
Daily log4.3/10
improving · -0.2 vs previous 14 d
Steps
Wearable10,284
improving · +443 vs previous 14 d
Adherence
Companion91.7 %
stable · +0.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 75 from the failing basin, 27 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More spicyGI -2.3 next day on high-intake days · n 13
Would not help
- Keep simple carbs lowGI +3.5 next day on high-intake days · n 18
- Keep alcohol lowGI +2.8 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+3.5detractor · 95%
- Alcohol+2.8detractor · 94%
- Spicy / capsaicin-2.3supporter · 75%
- Dietary fat load-0.9no signal · 23%
- Histamine load-0.3no signal · 15%
- Insoluble fibre-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.0 h, below personal baseline
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓20
- WearableShort sleep window
- Inflammatory signalling ↑15
- WearableHRV 34 ms, trending down
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.9 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 35 ms
- Sleep
- 6.2 h
- Steps
- 10,055
- Resting HR
- 62 bpm
Daily log: GI score 13, nutritional resilience 66, adherence 92.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.