Patient P-01350

Synthetic patientNBL-101 · Day 115 · 55–64 · F · baseline S19Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

16%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S19
Day 72 BR-03 recommended — Behavioural Recommendation BR-03
Day 73 Patient accepted — Started BR-03 in the companion
Day 80 No meaningful change — Behavioural Recommendation BR-03
Day 84 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 84.

Primary contributors, last 14 days

GI instability-14
Nutritional resilience+10
Inflammatory activity-3

What helped?

Behavioural Recommendation BR-03Day 72
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

16.4/100

improving · -1.9 vs previous 14 d

Toxicity

Blood

21.5/100

worsening · +0.9 vs previous 14 d

Sleep quality

Wearable

44.4/100

worsening · -2.4 vs previous 14 d

Energy level

Daily log

6.2/10

worsening · -0.4 vs previous 14 d

Stress level

Daily log

4/10

stable · +0.0 vs previous 14 d

Steps

Wearable

8,135

stable · +180 vs previous 14 d

Adherence

Companion

84.3 %

stable · -2.5 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 65 from the failing basin, 45 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5
Simple carbohydrates (supports)
perturbation · steering +5.9
Alcohol (supports)
perturbation · steering +5.6
Daily walks resumed
perturbation · steering +3.3
Simple carbohydrates
supporter · GI -3.9 next day
Alcohol
supporter · GI -3.8 next day

Main detractors to watch

Enterobacteriaceae elevated
hidden · steering -7.4
Antibiotic course
perturbation · steering -4.7
Dietary drift
perturbation · steering -2.6

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Simple carbohydrates
-3.9supporter · 71%
Alcohol
-3.8supporter · 74%
Spicy / capsaicin
-1.1no signal · 20%
Histamine load
-0.8no signal · 16%
Dietary fat load
-0.1no signal · 15%
Insoluble fibre
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↑25
- WearableResting HR 73 bpm

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.2 · butyrate capacity 53/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 48 ms
Sleep: 7.0 h
Steps: 9,930
Resting HR: 72 bpm

Daily log: GI score 16, nutritional resilience 67, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01679	49%	S12	AD-05	no change	39
P-01483	44%	S14	AD-05	no change	35
P-01541	44%	S09	AD-05	no change	43
P-01377	43%	S11	AD-05	no change	42
P-01848	41%	S05	AD-05	no change	23
P-01773	32%	S05	AD-05	improved	27
P-01804	31%	S19	AD-05	improved	61
P-01313	41%	S01	BR-03	improved	32
P-01450	38%	S09	BR-03	no change	36
P-01468	38%	S06	BR-03	no change	41
P-01689	35%	S13	BR-03	no change	50
P-01329	23%	S08	BR-03	improved	79