Patient P-01351

Synthetic patientNBL-101 · Day 119 · 45–54 · M · baseline S14Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Declining

Discontinuation risk

21%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S14
Day 17 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 17.

Primary contributors, last 14 days

Toxicity+14
GI instability-10
Inflammatory activity-7
Nutritional resilience-5
Treatment adherence-3

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

12.1/100

improving · -14.1 vs previous 14 d

Toxicity

Blood

20.4/100

worsening · +16.4 vs previous 14 d

Sleep quality

Wearable

37.4/100

improving · +3.3 vs previous 14 d

Energy level

Daily log

6.9/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

4/10

improving · -0.3 vs previous 14 d

Steps

Wearable

4,448

improving · +660 vs previous 14 d

Adherence

Companion

89.5 %

stable · -0.7 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 87 from the failing basin, 9 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep spicy low
GI +4.2 next day on high-intake days · n 20

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Spicy / capsaicin
+4.2detractor · 95%
Simple carbohydrates
-3no signal · 48%
Alcohol
-1.3no signal · 26%
Dietary fat load
-0.8no signal · 15%
Insoluble fibre
+0.7no signal · 17%
Histamine load
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓40
- DNAIL6 -174 variant raises baseline inflammatory tone
- WearableHRV 33 ms, trending down

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Intermediate metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.5 · butyrate capacity 46/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 33 ms
Sleep: 7.3 h
Steps: 4,347
Resting HR: 61 bpm

Daily log: GI score 12, nutritional resilience 63, adherence 90.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01804	32%	S19	AD-05	improved	61
P-01766	31%	S05	AD-05	no change	90
P-01495	37%	S07	BR-03	improved	85
P-01677	36%	S05	BR-03	no change	86
P-01329	34%	S08	BR-03	improved	79
P-01468	26%	S06	BR-03	no change	41
P-01654	36%	S08	CR-01	improved	85
P-01430	27%	S05	CR-01	improved	54
P-01479	36%	S15	DT-01	improved	84
P-01855	36%	S04	DT-01	improved	73
P-01767	33%	S14	DT-01	no change	63
P-01724	31%	S10	DT-01	improved	63