Patient P-01373
Synthetic patientNBL-101 · Day 92 · 25–34 · M · baseline S12Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S12
- Day 82 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 82 GI-04 recommended — GI Support Protocol GI-04
- Day 83 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 82.
Primary contributors, last 14 days
- GI instability+43
- Inflammatory activity+41
- Toxicity+32
- Nutritional resilience-23
- Treatment adherence-8
What helped?
- GI Support Protocol GI-04Day 82Declined by patient
LIFE OS recommendation
GI Support Protocol GI-04
65%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 86% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion71.3/100
worsening · +21.5 vs previous 14 d
Toxicity
Blood49.9/100
worsening · +15.2 vs previous 14 d
Sleep quality
Wearable19.1/100
worsening · -9.2 vs previous 14 d
Energy level
Daily log2.4/10
worsening · -1.7 vs previous 14 d
Stress level
Daily log6.7/10
worsening · +1.3 vs previous 14 d
Steps
Wearable300
worsening · -1,076 vs previous 14 d
Adherence
Companion80.9 %
stable · +1.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 37 from the failing basin, 72 from restoration.
Would help
Would not help
- Keep fat lowGI +4.7 next day on high-intake days · n 25
- Keep alcohol lowGI +4.7 next day on high-intake days · n 21
- Keep simple carbs lowGI +3.1 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.7detractor · 95%
- Alcohol+4.7detractor · 95%
- Simple carbohydrates+3.1detractor · 68%
- Spicy / capsaicin-2.7no signal · 42%
- Histamine load+1.6no signal · 33%
- Insoluble fibre-1.4no signal · 26%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 67
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 71 and rising
- WearableSleep 5.7 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 37/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓40
- Wearable300 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 50
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.1 · butyrate capacity 37/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 47 ms
- Sleep
- 6.1 h
- Steps
- 2,024
- Resting HR
- 62 bpm
Daily log: GI score 71, nutritional resilience 32, adherence 81.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01388 | 37% | S17 | CR-01 | improved | 59 |
| P-01371 | 36% | S06 | CR-01 | improved | 63 |
| P-01321 | 34% | S12 | GI-04 | improved | 53 |
| P-01696 | 33% | S20 | CR-01 | improved | 59 |
| P-01699 | 33% | S04 | GI-04 | improved | 69 |
| P-01835 | 31% | S17 | CR-01 | improved | 56 |
| P-01442 | 30% | S13 | CR-01 | improved | 61 |
| P-01614 | 29% | S14 | GI-04 | improved | 53 |
| P-01325 | 28% | S16 | GI-04 | improved | 54 |
| P-01339 | 28% | S14 | GI-04 | improved | 54 |
| P-01393 | 28% | S14 | GI-04 | improved | 53 |
| P-01511 | 28% | S14 | GI-04 | improved | 65 |