Patient P-01374

Synthetic patientNBL-101 · Day 115 · 45–54 · M · baseline S08Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

10%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S08
Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 14 HY-01 recommended — Hydration Protocol HY-01
Day 15 Patient accepted — Started HY-01 in the companion
Day 19 GI symptom burden −29% vs expected — Hydration Protocol HY-01
Day 25 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days

Nutritional resilience+6
GI instability-4
Toxicity+2

What helped?

Hydration Protocol HY-01Day 14
Result: symptom burden −29%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

17.5/100

worsening · +3.1 vs previous 14 d

Toxicity

Blood

10.5/100

improving · -6.3 vs previous 14 d

Sleep quality

Wearable

50.2/100

improving · +2.6 vs previous 14 d

Energy level

Daily log

6.6/10

stable · -0.2 vs previous 14 d

Stress level

Daily log

3.1/10

stable · +0.0 vs previous 14 d

Steps

Wearable

4,046

stable · -148 vs previous 14 d

Adherence

Companion

93.7 %

stable · -2.0 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 68 from the failing basin, 30 from restoration.

Good elements to keep

Hydration Protocol HY-01
intervention · steering +38.2

Main detractors to watch

Low butyrate capacity
hidden · steering -17.5
Poor metabolizer
hidden · steering -12.7
Low microbial diversity
hidden · steering -7.7
Bacteroides fragilis elevated
hidden · steering -7.4
Dietary fat load
detractor · GI +3.3 next day
Simple carbohydrates
detractor · GI +3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+3.3detractor · 95%
Simple carbohydrates
+3detractor · 94%
Histamine load
-1.1no signal · 25%
Spicy / capsaicin
+0.5no signal · 15%
Insoluble fibre
+0.2no signal · 15%
Alcohol
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 40/100
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose

Microbiome

Shannon diversity 2.1 · butyrate capacity 40/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 63 ms
Sleep: 6.3 h
Steps: 3,711
Resting HR: 69 bpm

Daily log: GI score 18, nutritional resilience 71, adherence 94.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01377	41%	S11	AD-05	no change	42
P-01541	39%	S09	AD-05	no change	43
P-01483	38%	S14	AD-05	no change	35
P-01679	34%	S12	AD-05	no change	39
P-01773	30%	S05	AD-05	improved	27
P-01804	30%	S19	AD-05	improved	61
P-01848	29%	S05	AD-05	no change	23
P-01313	37%	S01	BR-03	improved	32
P-01468	36%	S06	BR-03	no change	41
P-01350	35%	S19	BR-03	no change	34
P-01450	34%	S09	BR-03	no change	36
P-01689	34%	S13	BR-03	no change	50