Patient P-01375
Therapy response
Favorable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
35%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S16
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- GI instability+10
- Inflammatory activity+10
- Toxicity-4
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion29.1/100
worsening · +3.3 vs previous 14 d
Toxicity
Blood26.8/100
worsening · +4.8 vs previous 14 d
Sleep quality
Wearable38.4/100
worsening · -2.6 vs previous 14 d
Energy level
Daily log5/10
worsening · -0.4 vs previous 14 d
Stress level
Daily log3.6/10
worsening · +0.3 vs previous 14 d
Steps
Wearable6,130
worsening · -351 vs previous 14 d
Adherence
Companion91.4 %
stable · -2.7 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 62 from the failing basin, 25 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- Nothing clearly counter-productive in the record.
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load-1.7no signal · 24%
- Insoluble fibre-1.7no signal · 27%
- Simple carbohydrates+1.5no signal · 23%
- Spicy / capsaicin-1.5no signal · 23%
- Alcohol-0.8no signal · 15%
- Histamine load0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↓45
- WearableResting HR 76 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
- Mucosal barrier integrity ↓10
- WearableSleep 6.0 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 55/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 65 ms
- Sleep
- 6.5 h
- Steps
- 5,820
- Resting HR
- 78 bpm
Daily log: GI score 29, nutritional resilience 61, adherence 91.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01804 | 35% | S19 | AD-05 | improved | 61 |
| P-01377 | 34% | S11 | AD-05 | no change | 42 |
| P-01541 | 33% | S09 | AD-05 | no change | 43 |
| P-01483 | 31% | S14 | AD-05 | no change | 35 |
| P-01679 | 29% | S12 | AD-05 | no change | 39 |
| P-01689 | 38% | S13 | BR-03 | no change | 50 |
| P-01329 | 30% | S08 | BR-03 | improved | 79 |
| P-01677 | 29% | S05 | BR-03 | no change | 86 |
| P-01313 | 28% | S01 | BR-03 | improved | 32 |
| P-01350 | 28% | S19 | BR-03 | no change | 34 |
| P-01450 | 27% | S09 | BR-03 | no change | 36 |
| P-01468 | 27% | S06 | BR-03 | no change | 41 |