Patient P-01397

Synthetic patientNBL-101 · Day 110 · 35–44 · F · baseline S03Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

20%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S03
Day 80 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 80.

Primary contributors, last 14 days

Treatment adherence-7
Toxicity-4
GI instability+2
Inflammatory activity+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

23.7/100

worsening · +4.9 vs previous 14 d

Toxicity

Blood

8.1/100

improving · -5.8 vs previous 14 d

Sleep quality

Wearable

44.4/100

worsening · -7.3 vs previous 14 d

Energy level

Daily log

5.9/10

worsening · -0.4 vs previous 14 d

Stress level

Daily log

4.3/10

stable · -0.0 vs previous 14 d

Steps

Wearable

6,698

stable · -23 vs previous 14 d

Adherence

Companion

78.5 %

worsening · -8.1 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 64 from the failing basin, 50 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep alcohol low
GI +3.4 next day on high-intake days · n 16

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+3.4detractor · 95%
Dietary fat load
-1.6no signal · 39%
Spicy / capsaicin
-1.6no signal · 43%
Simple carbohydrates
+0.8no signal · 21%
Insoluble fibre
-0.4no signal · 15%
Histamine load
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↑15
- WearableHRV 34 ms, trending down

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.3 · butyrate capacity 61/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 32 ms
Sleep: 7.2 h
Steps: 6,077
Resting HR: 73 bpm

Daily log: GI score 24, nutritional resilience 66, adherence 79.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01483	40%	S14	AD-05	no change	35
P-01679	38%	S12	AD-05	no change	39
P-01541	37%	S09	AD-05	no change	43
P-01848	37%	S05	AD-05	no change	23
P-01377	36%	S11	AD-05	no change	42
P-01773	31%	S05	AD-05	improved	27
P-01804	27%	S19	AD-05	improved	61
P-01350	44%	S19	BR-03	no change	34
P-01313	40%	S01	BR-03	improved	32
P-01450	36%	S09	BR-03	no change	36
P-01468	32%	S06	BR-03	no change	41
P-01689	30%	S13	BR-03	no change	50