Patient P-01412
Therapy response
Improving
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
88%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 GI symptom burden −18% vs expected — Dietary Support Protocol NP-02
- Day 48 Tolerance state changed — Unstable → Improving
- Day 53 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 56 GI-04 recommended — GI Support Protocol GI-04
- Day 57 Patient accepted — Started GI-04 in the companion
- Day 65 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 53.
Primary contributors, last 14 days
- GI instability+10
- Inflammatory activity+6
- Nutritional resilience-5
- Toxicity+5
- Treatment adherence+2
What helped?
- Dietary Support Protocol NP-02Day 31Result: symptom burden −18%
- GI Support Protocol GI-04Day 56Result: no meaningful change
LIFE OS recommendation
Monitoring Escalation ME-01
91%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 67 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 40/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 60
- Autonomic recovery ↓25
- WearableResting HR 74 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 50
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3 · butyrate capacity 40/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 49 ms
- Sleep
- 6.8 h
- Steps
- 6,322
- Resting HR
- 73 bpm
Daily log: GI score 67, nutritional resilience 37, adherence 48.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01531 | 51% | S14 | ME-01 | improved | 51 |
| P-01656 | 51% | S14 | ME-01 | improved | 41 |
| P-01843 | 51% | S14 | SC-12 | no change | 45 |
| P-01598 | 50% | S14 | GI-04 | no change | 45 |
| P-01612 | 50% | S14 | ME-01 | improved | 51 |
| P-01728 | 50% | S14 | SC-12 | improved | 41 |
| P-01781 | 50% | S14 | NP-02 | improved | 45 |
| P-01842 | 50% | S14 | NP-02 | improved | 55 |
| P-01834 | 48% | S14 | NP-02 | improved | 44 |
| P-01360 | 47% | S14 | GI-04 | improved | 52 |
| P-01436 | 47% | S14 | GI-04 | improved | 38 |
| P-01581 | 47% | S18 | GI-04 | improved | 51 |