Patient P-01843
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 49 SC-12 recommended — Supportive Compound SC-12
- Day 50 Patient accepted — Started SC-12 in the companion
- Day 56 No meaningful change — Supportive Compound SC-12
What changed?
Trajectory began diverging from predicted response on Day 48.
Primary contributors, last 14 days
- Toxicity-12
- Inflammatory activity-6
- GI instability+4
- Nutritional resilience+2
What helped?
- Supportive Compound SC-12Day 49Result: no meaningful change
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 44/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 69 and rising
- Inflammatory signalling ↓25
- BloodInflammatory load index 58
- Drug metabolism and exposure ↑20
- BloodToxicity index 41
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 44/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 7.1 h
- Steps
- 4,751
- Resting HR
- 69 bpm
Daily log: GI score 69, nutritional resilience 38, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01656 | 63% | S14 | ME-01 | improved | 41 |
| P-01463 | 52% | S14 | NP-02 | no change | 41 |
| P-01595 | 52% | S14 | GI-04 | no change | 51 |
| P-01690 | 52% | S14 | — | — | 46 |
| P-01732 | 52% | S14 | ME-01 | improved | 45 |
| P-01751 | 52% | S14 | ME-01 | improved | 48 |
| P-01834 | 52% | S14 | NP-02 | improved | 44 |
| P-01412 | 51% | S14 | NP-02 | improved | 49 |
| P-01830 | 51% | S14 | — | — | 44 |
| P-01328 | 50% | S14 | SC-12 | no change | 49 |
| P-01646 | 50% | S14 | GI-04 | no change | 42 |
| P-01733 | 50% | S05 | SC-12 | no change | 49 |