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Patient P-01415

Synthetic patientNBL-101 · Day 112 · 65–74 · F · baseline S12Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S12
  2. Day 91 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 91.

Primary contributors, last 14 days
  • GI instability-9
  • Nutritional resilience+8
  • Inflammatory activity-7
  • Treatment adherence+6
  • Toxicity-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    20.4/100
    improving · -6.2 vs previous 14 d
    Toxicity
    Blood
    8.8/100
    improving · -1.1 vs previous 14 d
    Sleep quality
    Wearable
    49.5/100
    stable · +0.5 vs previous 14 d
    Energy level
    Daily log
    5.7/10
    stable · +0.0 vs previous 14 d
    Stress level
    Daily log
    2.5/10
    improving · -0.7 vs previous 14 d
    Steps
    Wearable
    9,344
    stable · +360 vs previous 14 d
    Adherence
    Companion
    85.6 %
    stable · +0.6 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 65 from the failing basin, 46 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Daily walks resumed
      perturbation · steering +3.3
    Main detractors to watch
    • FUT2 non-secretor
      hidden · steering -10.6
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • Histamine load
      perturbation · steering -6.7
    • Alcohol
      perturbation · steering -3.7
    • Histamine load
      detractor · GI +4.3 next day
    • Alcohol
      detractor · GI +2.5 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +4.3detractor · 95%
    • Alcohol
      +2.5detractor · 76%
    • Dietary fat load
      -1.5no signal · 36%
    • Insoluble fibre
      +1.4no signal · 32%
    • Simple carbohydrates
      +0.8no signal · 18%
    • Spicy / capsaicin
      -0.6no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Inflammatory signalling ↓20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Normal metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 4.6 · butyrate capacity 73/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    68 ms
    Sleep
    6.5 h
    Steps
    9,741
    Resting HR
    58 bpm
    Daily log: GI score 20, nutritional resilience 68, adherence 86.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0131350%S01BR-03improved32
    P-0186140%S12HY-01improved47
    P-0161839%S10GI-04improved39
    P-0132038%S09HY-01improved38
    P-0137436%S08HY-01improved49
    P-0173136%S01ME-01improved32
    P-0155535%S06GI-04improved56
    P-0138534%S06HY-01improved50
    P-0175234%S20DT-01improved50
    P-0134232%S11DT-01improved48
    P-0134632%S12DT-01improved52
    P-0145531%S01GI-04improved61