Patient P-01424

Synthetic patientNBL-101 · Day 101 · 45–54 · F · baseline S17Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Favorable

Discontinuation risk

24%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S17
Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 12.

Primary contributors, last 14 days

Toxicity-14
GI instability+10
Inflammatory activity+6
Nutritional resilience-2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

19.3/100

improving · -1.6 vs previous 14 d

Toxicity

Blood

11.6/100

stable · -0.6 vs previous 14 d

Sleep quality

Wearable

37.6/100

improving · +5.4 vs previous 14 d

Energy level

Daily log

5.4/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

4.5/10

stable · +0.1 vs previous 14 d

Steps

Wearable

8,046

worsening · -383 vs previous 14 d

Adherence

Companion

92.6 %

stable · +0.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 73 from the failing basin, 21 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep alcohol low
GI +5.4 next day on high-intake days · n 22
Keep fat low
GI +2.9 next day on high-intake days · n 13

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+5.4detractor · 95%
Dietary fat load
+2.9detractor · 73%
Spicy / capsaicin
-2no signal · 37%
Insoluble fibre
+0.9no signal · 15%
Simple carbohydrates
-0.3no signal · 15%
Histamine load
-0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↓20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

CYP2D6 Rapid metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.3 · butyrate capacity 79/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 48 ms
Sleep: 6.2 h
Steps: 8,321
Resting HR: 58 bpm

Daily log: GI score 19, nutritional resilience 64, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01430	44%	S05	CR-01	improved	54
P-01804	42%	S19	AD-05	improved	61
P-01571	39%	S13	SC-12	improved	57
P-01724	38%	S10	DT-01	improved	63
P-01593	37%	S10	HY-01	improved	56
P-01346	36%	S12	DT-01	improved	52
P-01555	36%	S06	GI-04	improved	56
P-01752	36%	S20	DT-01	improved	50
P-01861	36%	S12	HY-01	improved	47
P-01342	35%	S11	DT-01	improved	48
P-01385	35%	S06	HY-01	improved	50
P-01374	34%	S08	HY-01	improved	49