Patient P-01427

Synthetic patientNBL-101 · Day 118 · 45–54 · F · baseline S16Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Favorable

Nutritional resilience

Declining

Discontinuation risk

32%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S16
Day 25 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 25.

Primary contributors, last 14 days

GI instability+13
Nutritional resilience-6
Toxicity-6
Inflammatory activity+3
Treatment adherence+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

24.7/100

worsening · +4.5 vs previous 14 d

Toxicity

Blood

8.4/100

improving · -9.0 vs previous 14 d

Sleep quality

Wearable

29.2/100

worsening · -6.8 vs previous 14 d

Energy level

Daily log

5.9/10

stable · -0.1 vs previous 14 d

Stress level

Daily log

4.3/10

improving · -0.2 vs previous 14 d

Steps

Wearable

9,101

stable · -21 vs previous 14 d

Adherence

Companion

83.1 %

stable · -1.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 63 from the failing basin, 53 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep alcohol low
GI +3.5 next day on high-intake days · n 15
Keep spicy low
GI +2.6 next day on high-intake days · n 16

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+3.5detractor · 82%
Spicy / capsaicin
+2.6detractor · 58%
Histamine load
-1.1no signal · 24%
Simple carbohydrates
-0.9no signal · 20%
Dietary fat load
-0.5no signal · 15%
Insoluble fibre
-0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↓45
- WearableResting HR 73 bpm
- WearableShort sleep window
Inflammatory signalling ↑40
- DNAIL6 -174 variant raises baseline inflammatory tone
- WearableHRV 31 ms, trending down

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Rapid metabolizer
Expected exposure

Microbiome

Shannon diversity 4.4 · butyrate capacity 57/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 33 ms
Sleep: 6.7 h
Steps: 9,554
Resting HR: 74 bpm

Daily log: GI score 25, nutritional resilience 65, adherence 83.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01773	37%	S05	AD-05	improved	27
P-01483	30%	S14	AD-05	no change	35
P-01377	29%	S11	AD-05	no change	42
P-01679	29%	S12	AD-05	no change	39
P-01848	29%	S05	AD-05	no change	23
P-01541	28%	S09	AD-05	no change	43
P-01804	24%	S19	AD-05	improved	61
P-01313	33%	S01	BR-03	improved	32
P-01350	30%	S19	BR-03	no change	34
P-01450	28%	S09	BR-03	no change	36
P-01468	26%	S06	BR-03	no change	41
P-01689	24%	S13	BR-03	no change	50