Patient P-01429
Synthetic patientNBL-101 · Day 115 · 45–54 · F · baseline S09Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Stable
Inflammatory state
Stable
Nutritional resilience
Improving
Discontinuation risk
56%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S09
- Day 49 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 60 GI-04 recommended — GI Support Protocol GI-04
- Day 61 Patient accepted — Started GI-04 in the companion
- Day 69 GI symptom burden −32% vs expected — GI Support Protocol GI-04
- Day 75 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 49.
Primary contributors, last 14 days
- Nutritional resilience+8
- Inflammatory activity-3
- Toxicity-2
What helped?
- GI Support Protocol GI-04Day 60Result: symptom burden −32%
LIFE OS recommendation
Dietary Support Protocol NP-02
55%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion53.3/100
stable · -0.5 vs previous 14 d
Toxicity
Blood41.5/100
improving · -3.4 vs previous 14 d
Sleep quality
Wearable17.8/100
worsening · -2.0 vs previous 14 d
Energy level
Daily log3.3/10
stable · +0.0 vs previous 14 d
Stress level
Daily log6/10
improving · -0.4 vs previous 14 d
Steps
Wearable2,095
worsening · -115 vs previous 14 d
Adherence
Companion48.6 %
stable · +0.6 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 29 from the failing basin, 58 from restoration.
Good elements to keep
- GI Support Protocol GI-04intervention · steering +51.1
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Poor metabolizerhidden · steering -12.7
- Dietary fat loadperturbation · steering -9.8
- Simple carbohydratesperturbation · steering -9.2
- Dietary fat loaddetractor · GI +5.5 next day
- Simple carbohydratesdetractor · GI +5.4 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.5detractor · 95%
- Simple carbohydrates+5.4detractor · 95%
- Spicy / capsaicin+1.8no signal · 39%
- Histamine load+1.6no signal · 32%
- Insoluble fibre+1.1no signal · 23%
- Alcohol-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 33/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓65
- WearableResting HR 75 bpm
- Wearable2,095 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 42
- Inflammatory signalling ↓40
- BloodInflammatory load index 55
- WearableHRV 26 ms, trending down
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 53 and rising
- WearableSleep 5.5 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 2.8 · butyrate capacity 33/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 30 ms
- Sleep
- 6.0 h
- Steps
- 1,881
- Resting HR
- 76 bpm
Daily log: GI score 53, nutritional resilience 45, adherence 49.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01804 | 22% | S19 | AD-05 | improved | 61 |
| P-01377 | 21% | S11 | AD-05 | no change | 42 |
| P-01350 | 21% | S19 | BR-03 | no change | 34 |
| P-01708 | 31% | S07 | CR-01 | improved | 59 |
| P-01371 | 30% | S06 | CR-01 | improved | 63 |
| P-01696 | 30% | S20 | CR-01 | improved | 59 |
| P-01835 | 30% | S17 | CR-01 | improved | 56 |
| P-01388 | 28% | S17 | CR-01 | improved | 59 |
| P-01442 | 28% | S13 | CR-01 | improved | 61 |
| P-01877 | 27% | S01 | CR-01 | improved | 67 |
| P-01430 | 23% | S05 | CR-01 | improved | 54 |
| P-01342 | 21% | S11 | DT-01 | improved | 48 |