Patient P-01440
Synthetic patientNBL-101 · Day 115 · 45–54 · M · baseline S12Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
71%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S12
- Day 49 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 52 GI-04 recommended — GI Support Protocol GI-04
- Day 53 Patient accepted — Started GI-04 in the companion
- Day 61 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 49.
Primary contributors, last 14 days
- Nutritional resilience+7
- Treatment adherence+6
- Toxicity+4
- GI instability-2
- Inflammatory activity-2
What helped?
- GI Support Protocol GI-04Day 52Result: no meaningful change
LIFE OS recommendation
Dietary Support Protocol NP-02
61%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion71.5/100
improving · -7.5 vs previous 14 d
Toxicity
Blood55.5/100
worsening · +6.0 vs previous 14 d
Sleep quality
Wearable11.9/100
improving · +5.1 vs previous 14 d
Energy level
Daily log2.1/10
improving · +0.4 vs previous 14 d
Stress level
Daily log7/10
improving · -0.6 vs previous 14 d
Steps
Wearable3,470
stable · +132 vs previous 14 d
Adherence
Companion46.6 %
improving · +4.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading drifting · 28 from the failing basin, 77 from restoration.
Would help
Would not help
- GI-04 GI Support Protocolalready tried, no meaningful change
- Keep histamine lowGI +3.2 next day on high-intake days · n 20
- Keep simple carbs lowGI +3.1 next day on high-intake days · n 12
- Keep fat lowGI +2.5 next day on high-intake days · n 16
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+3.2detractor · 95%
- Simple carbohydrates+3.1detractor · 95%
- Dietary fat load+2.5detractor · 84%
- Insoluble fibre-1.3no signal · 42%
- Alcohol+1.3no signal · 42%
- Spicy / capsaicin-0.9no signal · 26%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↑65
- WearableResting HR 74 bpm
- Wearable3,470 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 72 and rising
- WearableSleep 5.1 h, below personal baseline
- Inflammatory signalling ↓60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 70
- WearableHRV 31 ms, trending down
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 56
- Butyrate / short-chain fatty acid production ↓20
- Daily logFibre intake low in recent food logs
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 2.6 · butyrate capacity 45/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 30 ms
- Sleep
- 5.4 h
- Steps
- 3,689
- Resting HR
- 72 bpm
Daily log: GI score 72, nutritional resilience 37, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01772 | 53% | S20 | NP-02 | no change | 50 |
| P-01367 | 50% | S14 | GI-04 | no change | 51 |
| P-01736 | 50% | S03 | ME-01 | improved | 46 |
| P-01582 | 49% | S14 | GI-04 | no change | 45 |
| P-01652 | 48% | S12 | ME-01 | improved | 44 |
| P-01830 | 48% | S14 | — | — | 44 |
| P-01841 | 48% | S14 | — | — | 48 |
| P-01615 | 47% | S14 | ME-01 | improved | 48 |
| P-01728 | 47% | S14 | SC-12 | improved | 41 |
| P-01531 | 46% | S14 | ME-01 | improved | 51 |
| P-01776 | 46% | S16 | NP-02 | no change | 47 |
| P-01572 | 45% | S14 | GI-04 | worsened | 41 |