Patient P-01443

Synthetic patientNBL-101 · Day 110 · 65–74 · F · baseline S03Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Deteriorating

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

30%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S03
Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 16.

Primary contributors, last 14 days

Nutritional resilience-10
GI instability+8
Toxicity+7
Inflammatory activity+5
Treatment adherence-4

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

20/100

worsening · +4.5 vs previous 14 d

Toxicity

Blood

28.5/100

worsening · +4.3 vs previous 14 d

Sleep quality

Wearable

61.6/100

stable · -1.5 vs previous 14 d

Energy level

Daily log

5.5/10

worsening · -0.5 vs previous 14 d

Stress level

Daily log

3.4/10

stable · +0.0 vs previous 14 d

Steps

Wearable

2,503

stable · -51 vs previous 14 d

Adherence

Companion

82.2 %

stable · +0.8 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 62 from the failing basin, 47 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep spicy low
GI +2.6 next day on high-intake days · n 12

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Spicy / capsaicin
+2.6detractor · 65%
Histamine load
-1.5no signal · 48%
Simple carbohydrates
+1.3no signal · 33%
Insoluble fibre
-0.7no signal · 16%
Alcohol
+0.5no signal · 15%
Dietary fat load
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↓45
- WearableResting HR 73 bpm
- Wearable2,503 steps/day
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted

DNA

Fictional pharmacogenomic panel

CYP2D6 Intermediate metabolizer
Expected exposure

Microbiome

Shannon diversity 4.4 · butyrate capacity 69/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 60 ms
Sleep: 7.9 h
Steps: 3,496
Resting HR: 72 bpm

Daily log: GI score 20, nutritional resilience 60, adherence 82.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01773	45%	S05	AD-05	improved	27
P-01679	39%	S12	AD-05	no change	39
P-01377	37%	S11	AD-05	no change	42
P-01483	37%	S14	AD-05	no change	35
P-01848	35%	S05	AD-05	no change	23
P-01541	33%	S09	AD-05	no change	43
P-01804	26%	S19	AD-05	improved	61
P-01313	37%	S01	BR-03	improved	32
P-01350	36%	S19	BR-03	no change	34
P-01450	36%	S09	BR-03	no change	36
P-01689	31%	S13	BR-03	no change	50
P-01468	30%	S06	BR-03	no change	41