Patient P-01450

Synthetic patientNBL-101 · Day 120 · 25–34 · M · baseline S09Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

11%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S09
Day 72 BR-03 recommended — Behavioural Recommendation BR-03
Day 73 Patient accepted — Started BR-03 in the companion
Day 80 No meaningful change — Behavioural Recommendation BR-03
Day 81 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 81.

Primary contributors, last 14 days

GI instability-10
Nutritional resilience+8
Inflammatory activity-7
Toxicity+3

What helped?

Behavioural Recommendation BR-03Day 72
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

8.7/100

improving · -10.3 vs previous 14 d

Toxicity

Blood

14.7/100

improving · -2.3 vs previous 14 d

Sleep quality

Wearable

64.5/100

improving · +6.8 vs previous 14 d

Energy level

Daily log

6.6/10

improving · +0.6 vs previous 14 d

Stress level

Daily log

2.7/10

improving · -0.3 vs previous 14 d

Steps

Wearable

6,149

improving · +339 vs previous 14 d

Adherence

Companion

80.1 %

stable · -0.9 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 79 from the failing basin, 44 from restoration.

Good elements to keep

Behavioural Recommendation BR-03
intervention · steering +7.5
Butyrate producers intact
hidden · steering +7.5
Daily walks resumed
perturbation · steering +3.3

Main detractors to watch

FUT2 non-secretor
hidden · steering -10.6
Histamine load
perturbation · steering -7.1
Antibiotic course
perturbation · steering -4.7
Poor-sleep week
perturbation · steering -3
Histamine load
detractor · GI +4.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+4.3detractor · 95%
Insoluble fibre
-1.4no signal · 31%
Simple carbohydrates
+0.2no signal · 15%
Alcohol
+0.1no signal · 15%
Spicy / capsaicin
-0.1no signal · 15%
Dietary fat load
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↓25
- WearableResting HR 72 bpm

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.7 · butyrate capacity 76/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 66 ms
Sleep: 7.0 h
Steps: 6,627
Resting HR: 72 bpm

Daily log: GI score 9, nutritional resilience 71, adherence 80.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01377	46%	S11	AD-05	no change	42
P-01483	42%	S14	AD-05	no change	35
P-01541	40%	S09	AD-05	no change	43
P-01679	39%	S12	AD-05	no change	39
P-01848	37%	S05	AD-05	no change	23
P-01773	33%	S05	AD-05	improved	27
P-01804	25%	S19	AD-05	improved	61
P-01313	44%	S01	BR-03	improved	32
P-01468	43%	S06	BR-03	no change	41
P-01350	38%	S19	BR-03	no change	34
P-01689	34%	S13	BR-03	no change	50
P-01430	28%	S05	CR-01	improved	54