Patient P-01455

Synthetic patientNBL-101 · Day 115 · 75+ · M · baseline S01Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Favorable

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S01
Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 14 GI-04 recommended — GI Support Protocol GI-04
Day 15 Patient accepted — Started GI-04 in the companion
Day 23 GI symptom burden −15% vs expected — GI Support Protocol GI-04
Day 29 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days

GI instability-8
Inflammatory activity-3
Nutritional resilience+3

What helped?

GI Support Protocol GI-04Day 14
Result: symptom burden −15%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

13.6/100

improving · -9.1 vs previous 14 d

Toxicity

Blood

24.4/100

worsening · +6.9 vs previous 14 d

Sleep quality

Wearable

60.7/100

improving · +5.2 vs previous 14 d

Energy level

Daily log

6.7/10

improving · +0.5 vs previous 14 d

Stress level

Daily log

4/10

stable · -0.1 vs previous 14 d

Steps

Wearable

6,366

improving · +208 vs previous 14 d

Adherence

Companion

90.2 %

stable · -3.2 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 79 from the failing basin, 18 from restoration.

Good elements to keep

GI Support Protocol GI-04
intervention · steering +19.8

Main detractors to watch

Low butyrate capacity
hidden · steering -17.5
Dietary fat load
perturbation · steering -8.8
Low microbial diversity
hidden · steering -7.7
Enterobacteriaceae elevated
hidden · steering -7.4
Dietary fat load
detractor · GI +5.1 next day
Simple carbohydrates
detractor · GI +3.6 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+5.1detractor · 95%
Simple carbohydrates
+3.6detractor · 95%
Insoluble fibre
-0.8no signal · 15%
Spicy / capsaicin
-0.6no signal · 15%
Histamine load
+0.5no signal · 15%
Alcohol
-0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 35/100
Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
Autonomic recovery ↑25
- WearableResting HR 72 bpm

DNA

Fictional pharmacogenomic panel

DPYD *2A heterozygous
Slower drug clearance
CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.2 · butyrate capacity 35/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 55 ms
Sleep: 6.8 h
Steps: 4,869
Resting HR: 74 bpm

Daily log: GI score 14, nutritional resilience 65, adherence 90.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01377	37%	S11	AD-05	no change	42
P-01541	33%	S09	AD-05	no change	43
P-01483	32%	S14	AD-05	no change	35
P-01679	32%	S12	AD-05	no change	39
P-01804	32%	S19	AD-05	improved	61
P-01468	35%	S06	BR-03	no change	41
P-01689	35%	S13	BR-03	no change	50
P-01450	33%	S09	BR-03	no change	36
P-01313	31%	S01	BR-03	improved	32
P-01350	31%	S19	BR-03	no change	34
P-01677	28%	S05	BR-03	no change	86
P-01329	27%	S08	BR-03	improved	79