Patient P-01479
Synthetic patientNBL-101 · Day 96 · 45–54 · M · baseline S15Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
15%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S15
- Day 18 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 25 DT-01 recommended — Dosing / Timing Recommendation DT-01
- Day 26 Patient accepted — Started DT-01 in the companion
- Day 31 GI symptom burden −14% vs expected — Dosing / Timing Recommendation DT-01
- Day 37 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 18.
Primary contributors, last 14 days
- Toxicity-10
- GI instability+5
What helped?
- Dosing / Timing Recommendation DT-01Day 25Result: symptom burden −14%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion13.5/100
improving · -1.7 vs previous 14 d
Toxicity
Blood14.2/100
improving · -3.5 vs previous 14 d
Sleep quality
Wearable54.2/100
stable · +1.8 vs previous 14 d
Energy level
Daily log6.7/10
improving · +0.4 vs previous 14 d
Stress level
Daily log3.5/10
improving · -0.5 vs previous 14 d
Steps
Wearable2,818
worsening · -416 vs previous 14 d
Adherence
Companion94.2 %
worsening · -5.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 92 from the failing basin, 8 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- Keep histamine lowGI +6.3 next day on high-intake days · n 16
- Keep simple carbs lowGI +4 next day on high-intake days · n 11
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+6.3detractor · 95%
- Simple carbohydrates+4detractor · 92%
- Alcohol+1.2no signal · 27%
- Dietary fat load+1no signal · 23%
- Spicy / capsaicin-0.2no signal · 15%
- Insoluble fibre0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↑20
- Wearable2,818 steps/day
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.8 · butyrate capacity 68/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 57 ms
- Sleep
- 6.9 h
- Steps
- 3,586
- Resting HR
- 61 bpm
Daily log: GI score 14, nutritional resilience 70, adherence 94.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.