Patient P-01481
Synthetic patientNBL-101 · Day 110 · 45–54 · F · baseline S03Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Stable
Discontinuation risk
31%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S03
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- Treatment adherence-3
- Toxicity-3
- GI instability+2
- Nutritional resilience-2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion35.4/100
worsening · +7.9 vs previous 14 d
Toxicity
Blood30.6/100
worsening · +9.9 vs previous 14 d
Sleep quality
Wearable47.9/100
worsening · -8.0 vs previous 14 d
Energy level
Daily log5.1/10
worsening · -1.1 vs previous 14 d
Stress level
Daily log5.7/10
worsening · +1.0 vs previous 14 d
Steps
Wearable6,058
worsening · -695 vs previous 14 d
Adherence
Companion87 %
worsening · -3.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 53 from the failing basin, 34 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- Keep alcohol lowGI +5.9 next day on high-intake days · n 14
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Alcohol+5.9detractor · 95%
- Histamine load+1.6no signal · 25%
- Insoluble fibre+0.9no signal · 20%
- Simple carbohydrates-0.7no signal · 15%
- Spicy / capsaicin-0.6no signal · 15%
- Dietary fat load+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑75
- DNACYP2D6 poor metabolizer → higher exposure
- DNADPYD *2A → slower clearance
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓25
- WearableResting HR 73 bpm
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 4.1 · butyrate capacity 47/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 45 ms
- Sleep
- 7.4 h
- Steps
- 5,466
- Resting HR
- 74 bpm
Daily log: GI score 35, nutritional resilience 54, adherence 87.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.