Patient P-01481

Synthetic patientNBL-101 · Day 110 · 45–54 · F · baseline S03Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Stable

Discontinuation risk

31%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S03

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Treatment adherence-3
Toxicity-3
GI instability+2
Nutritional resilience-2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

35.4/100

worsening · +7.9 vs previous 14 d

Toxicity

Blood

30.6/100

worsening · +9.9 vs previous 14 d

Sleep quality

Wearable

47.9/100

worsening · -8.0 vs previous 14 d

Energy level

Daily log

5.1/10

worsening · -1.1 vs previous 14 d

Stress level

Daily log

5.7/10

worsening · +1.0 vs previous 14 d

Steps

Wearable

6,058

worsening · -695 vs previous 14 d

Adherence

Companion

87 %

worsening · -3.8 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 53 from the failing basin, 34 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep alcohol low
GI +5.9 next day on high-intake days · n 14

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+5.9detractor · 95%
Histamine load
+1.6no signal · 25%
Insoluble fibre
+0.9no signal · 20%
Simple carbohydrates
-0.7no signal · 15%
Spicy / capsaicin
-0.6no signal · 15%
Dietary fat load
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑75
- DNACYP2D6 poor metabolizer → higher exposure
- DNADPYD *2A → slower clearance
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↓25
- WearableResting HR 73 bpm
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

DPYD *2A heterozygous
Slower drug clearance
CYP2D6 Poor metabolizer
Higher exposure at standard dose
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.1 · butyrate capacity 47/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 45 ms
Sleep: 7.4 h
Steps: 5,466
Resting HR: 74 bpm

Daily log: GI score 35, nutritional resilience 54, adherence 87.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01804	45%	S19	AD-05	improved	61
P-01541	34%	S09	AD-05	no change	43
P-01679	33%	S12	AD-05	no change	39
P-01377	32%	S11	AD-05	no change	42
P-01483	31%	S14	AD-05	no change	35
P-01689	36%	S13	BR-03	no change	50
P-01350	33%	S19	BR-03	no change	34
P-01329	29%	S08	BR-03	improved	79
P-01313	28%	S01	BR-03	improved	32
P-01468	28%	S06	BR-03	no change	41
P-01430	39%	S05	CR-01	improved	54
P-01371	32%	S06	CR-01	improved	63