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Patient P-01487

Synthetic patientNBL-101 · Day 92 · 35–44 · F · baseline S03Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Declining
Discontinuation risk
14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S03
  2. Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days
  • Inflammatory activity-7
  • Treatment adherence-6
  • GI instability-4
  • Nutritional resilience-4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    16.1/100
    improving · -1.8 vs previous 14 d
    Toxicity
    Blood
    19.9/100
    stable · +0.1 vs previous 14 d
    Sleep quality
    Wearable
    36.1/100
    improving · +1.8 vs previous 14 d
    Energy level
    Daily log
    5.4/10
    stable · +0.1 vs previous 14 d
    Stress level
    Daily log
    4.2/10
    stable · -0.2 vs previous 14 d
    Steps
    Wearable
    2,814
    worsening · -344 vs previous 14 d
    Adherence
    Companion
    87.7 %
    stable · -1.5 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 74 from the failing basin, 30 from restoration.

    Good elements to keep
    • Daily walks resumed
      perturbation · steering +3.3
    Main detractors to watch
    • Low butyrate capacity
      hidden · steering -17.5
    • Dietary fat load
      perturbation · steering -8
    • Low microbial diversity
      hidden · steering -7.7
    • Enterobacteriaceae elevated
      hidden · steering -7.4
    • Dietary fat load
      detractor · GI +4.9 next day
    • Alcohol
      detractor · GI +4.8 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Dietary fat load
      +4.9detractor · 95%
    • Alcohol
      +4.8detractor · 95%
    • Simple carbohydrates
      +3.4detractor · 95%
    • Spicy / capsaicin
      -0.8no signal · 16%
    • Histamine load
      -0.7no signal · 15%
    • Insoluble fibre
      +0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Butyrate / short-chain fatty acid production ↓60
      • MicrobiomeButyrate capacity 24/100
      • MicrobiomeF. prausnitzii depleted
    • Mucosal barrier integrity ↓40
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.7 h, below personal baseline
    • Autonomic recovery ↑40
      • Wearable2,814 steps/day
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2.9 · butyrate capacity 24/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    45 ms
    Sleep
    6.4 h
    Steps
    2,963
    Resting HR
    71 bpm
    Daily log: GI score 16, nutritional resilience 64, adherence 88.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
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    P-0154142%S09AD-05no change43
    P-0137741%S11AD-05no change42
    P-0148340%S14AD-05no change35
    P-0167938%S12AD-05no change39
    P-0180435%S19AD-05improved61
    P-0177332%S05AD-05improved27
    P-0184830%S05AD-05no change23
    P-0135039%S19BR-03no change34
    P-0131338%S01BR-03improved32
    P-0146837%S06BR-03no change41
    P-0145036%S09BR-03no change36
    P-0168935%S13BR-03no change50