Patient P-01494
Synthetic patientNBL-101 · Day 95 · 35–44 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Stable
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
68%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 45 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 52 SC-12 recommended — Supportive Compound SC-12
- Day 53 Patient declined — Not now
- Day 56 GI-04 recommended — GI Support Protocol GI-04
- Day 57 Patient accepted — Started GI-04 in the companion
- Day 65 GI symptom burden −23% vs expected — GI Support Protocol GI-04
- Day 71 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 45.
Primary contributors, last 14 days
- Inflammatory activity-13
- Toxicity-13
- Nutritional resilience+5
- Treatment adherence-5
- GI instability-2
What helped?
- Supportive Compound SC-12Day 52Declined by patient
- GI Support Protocol GI-04Day 56Result: symptom burden −23%
LIFE OS recommendation
Dietary Support Protocol NP-02
53%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion56.1/100
improving · -2.5 vs previous 14 d
Toxicity
Blood44.8/100
worsening · +2.8 vs previous 14 d
Sleep quality
Wearable44.8/100
improving · +2.1 vs previous 14 d
Energy level
Daily log3.6/10
improving · +0.2 vs previous 14 d
Stress level
Daily log5.4/10
stable · -0.2 vs previous 14 d
Steps
Wearable1,865
stable · +44 vs previous 14 d
Adherence
Companion48.8 %
worsening · -12.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 26 from the failing basin, 61 from restoration.
Would help
Would not help
- Keep fat lowGI +3.1 next day on high-intake days · n 27
- Keep spicy lowGI +3.1 next day on high-intake days · n 17
- Keep simple carbs lowGI +1.9 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+3.1detractor · 95%
- Spicy / capsaicin+3.1detractor · 95%
- Simple carbohydrates+1.9detractor · 71%
- Alcohol+1no signal · 21%
- Insoluble fibre+0.7no signal · 26%
- Histamine load+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 53
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 45
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 23/100
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 56 and rising
- Autonomic recovery ↑20
- Wearable1,865 steps/day
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 2.3 · butyrate capacity 23/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 47 ms
- Sleep
- 6.8 h
- Steps
- 2,085
- Resting HR
- 71 bpm
Daily log: GI score 56, nutritional resilience 43, adherence 49.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01377 | 21% | S11 | AD-05 | no change | 42 |
| P-01483 | 21% | S14 | AD-05 | no change | 35 |
| P-01689 | 22% | S13 | BR-03 | no change | 50 |
| P-01708 | 32% | S07 | CR-01 | improved | 59 |
| P-01371 | 29% | S06 | CR-01 | improved | 63 |
| P-01696 | 28% | S20 | CR-01 | improved | 59 |
| P-01835 | 27% | S17 | CR-01 | improved | 56 |
| P-01388 | 26% | S17 | CR-01 | improved | 59 |
| P-01442 | 26% | S13 | CR-01 | improved | 61 |
| P-01877 | 26% | S01 | CR-01 | improved | 67 |
| P-01430 | 22% | S05 | CR-01 | improved | 54 |
| P-01342 | 21% | S11 | DT-01 | improved | 48 |