Patient P-01501
Synthetic patientNBL-101 · Day 101 · 65–74 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
59%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 52 SC-12 recommended — Supportive Compound SC-12
- Day 53 Patient accepted — Started SC-12 in the companion
- Day 58 GI-04 recommended — GI Support Protocol GI-04
- Day 59 Patient accepted — Started GI-04 in the companion
- Day 59 GI symptom burden −18% vs expected — Supportive Compound SC-12
- Day 65 Tolerance state changed — Unstable → Improving
- Day 67 GI symptom burden −23% vs expected — GI Support Protocol GI-04
- Day 73 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- GI instability-14
- Toxicity+14
- Treatment adherence+9
- Inflammatory activity-5
- Nutritional resilience+5
What helped?
- Supportive Compound SC-12Day 52Result: symptom burden −18%
- GI Support Protocol GI-04Day 58Result: symptom burden −23%
LIFE OS recommendation
Dietary Support Protocol NP-02
53%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion40.4/100
stable · +0.0 vs previous 14 d
Toxicity
Blood45.6/100
worsening · +6.6 vs previous 14 d
Sleep quality
Wearable24.3/100
stable · -0.2 vs previous 14 d
Energy level
Daily log3.5/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log6.1/10
stable · +0.0 vs previous 14 d
Steps
Wearable5,174
worsening · -577 vs previous 14 d
Adherence
Companion52.4 %
worsening · -5.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 40 from the failing basin, 47 from restoration.
Would help
Would not help
- Keep simple carbs lowGI +5.2 next day on high-intake days · n 19
- Keep fat lowGI +4 next day on high-intake days · n 17
- Keep histamine lowGI +3.5 next day on high-intake days · n 24
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+5.2detractor · 95%
- Dietary fat load+4detractor · 88%
- Histamine load+3.5detractor · 88%
- Spicy / capsaicin-2.9no signal · 54%
- Alcohol+1no signal · 19%
- Insoluble fibre+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 47
- WearableHRV 30 ms, trending down
- Mucosal barrier integrity ↓70
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.8 h, below personal baseline
- Autonomic recovery ↑45
- WearableResting HR 80 bpm
- WearableShort sleep window
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 44/100
- Drug metabolism and exposure ↑20
- BloodToxicity index 46
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.8 · butyrate capacity 44/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 28 ms
- Sleep
- 6.0 h
- Steps
- 4,655
- Resting HR
- 83 bpm
Daily log: GI score 40, nutritional resilience 50, adherence 52.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01804 | 23% | S19 | AD-05 | improved | 61 |
| P-01696 | 29% | S20 | CR-01 | improved | 59 |
| P-01371 | 28% | S06 | CR-01 | improved | 63 |
| P-01708 | 28% | S07 | CR-01 | improved | 59 |
| P-01442 | 27% | S13 | CR-01 | improved | 61 |
| P-01835 | 26% | S17 | CR-01 | improved | 56 |
| P-01388 | 25% | S17 | CR-01 | improved | 59 |
| P-01430 | 25% | S05 | CR-01 | improved | 54 |
| P-01877 | 24% | S01 | CR-01 | improved | 67 |
| P-01767 | 23% | S14 | DT-01 | no change | 63 |
| P-01323 | 51% | S14 | GI-04 | improved | 50 |
| P-01573 | 50% | S14 | GI-04 | improved | 49 |