Patient P-01513

Synthetic patientNBL-101 · Day 90 · 65–74 · M · baseline S19Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Declining

Discontinuation risk

10%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S19
Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 14 GI-04 recommended — GI Support Protocol GI-04
Day 15 Patient accepted — Started GI-04 in the companion
Day 23 No meaningful change — GI Support Protocol GI-04

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days

Inflammatory activity-11
GI instability-8
Nutritional resilience-5
Toxicity+4

What helped?

GI Support Protocol GI-04Day 14
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

15.3/100

improving · -2.2 vs previous 14 d

Toxicity

Blood

13.6/100

improving · -3.5 vs previous 14 d

Sleep quality

Wearable

54.5/100

stable · +0.2 vs previous 14 d

Energy level

Daily log

6.8/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

3.2/10

improving · -0.2 vs previous 14 d

Steps

Wearable

6,213

improving · +789 vs previous 14 d

Adherence

Companion

90.5 %

stable · -1.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 78 from the failing basin, 26 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

GI-04 GI Support Protocol
already tried, no meaningful change
Keep simple carbs low
GI +7 next day on high-intake days · n 18

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Simple carbohydrates
+7detractor · 95%
Histamine load
-2.5no signal · 36%
Dietary fat load
+2.2no signal · 37%
Spicy / capsaicin
-1.5no signal · 21%
Insoluble fibre
-0.9no signal · 15%
Alcohol
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

DPYD *2A heterozygous
Slower drug clearance
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 2.5 · butyrate capacity 47/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 70 ms
Sleep: 6.9 h
Steps: 6,517
Resting HR: 68 bpm

Daily log: GI score 15, nutritional resilience 59, adherence 91.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01377	36%	S11	AD-05	no change	42
P-01541	36%	S09	AD-05	no change	43
P-01483	35%	S14	AD-05	no change	35
P-01679	33%	S12	AD-05	no change	39
P-01773	28%	S05	AD-05	improved	27
P-01804	28%	S19	AD-05	improved	61
P-01848	28%	S05	AD-05	no change	23
P-01468	35%	S06	BR-03	no change	41
P-01313	33%	S01	BR-03	improved	32
P-01450	33%	S09	BR-03	no change	36
P-01689	33%	S13	BR-03	no change	50
P-01350	32%	S19	BR-03	no change	34