Patient P-01519

Synthetic patientNBL-101 · Day 119 · 25–34 · M · baseline S06Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Favorable

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

12%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S06
Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 12.

Primary contributors, last 14 days

GI instability-7
Inflammatory activity-7
Nutritional resilience+7
Treatment adherence+5
Toxicity+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

15.7/100

worsening · +5.1 vs previous 14 d

Toxicity

Blood

16.4/100

stable · -0.6 vs previous 14 d

Sleep quality

Wearable

52.1/100

worsening · -2.6 vs previous 14 d

Energy level

Daily log

6.5/10

worsening · -0.3 vs previous 14 d

Stress level

Daily log

4.4/10

worsening · +0.3 vs previous 14 d

Steps

Wearable

9,294

worsening · -601 vs previous 14 d

Adherence

Companion

89 %

worsening · -5.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 74 from the failing basin, 31 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep simple carbs low
GI +2.4 next day on high-intake days · n 22
Keep spicy low
GI +2.4 next day on high-intake days · n 20

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Simple carbohydrates
+2.4detractor · 84%
Spicy / capsaicin
+2.4detractor · 88%
Histamine load
-1.4no signal · 36%
Dietary fat load
-1.2no signal · 29%
Insoluble fibre
+0.8no signal · 17%
Alcohol
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 36 ms, trending down
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 1.9 · butyrate capacity 45/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 36 ms
Sleep: 7.5 h
Steps: 9,566
Resting HR: 64 bpm

Daily log: GI score 16, nutritional resilience 70, adherence 89.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01541	37%	S09	AD-05	no change	43
P-01377	36%	S11	AD-05	no change	42
P-01483	36%	S14	AD-05	no change	35
P-01679	36%	S12	AD-05	no change	39
P-01804	35%	S19	AD-05	improved	61
P-01773	32%	S05	AD-05	improved	27
P-01848	29%	S05	AD-05	no change	23
P-01350	37%	S19	BR-03	no change	34
P-01468	36%	S06	BR-03	no change	41
P-01313	35%	S01	BR-03	improved	32
P-01450	32%	S09	BR-03	no change	36
P-01689	31%	S13	BR-03	no change	50