Patient P-01541

Synthetic patientNBL-101 · Day 115 · 25–34 · M · baseline S09Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Improving

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Favorable

Discontinuation risk

13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S09
Day 72 AD-05 recommended — Adherence Support AD-05
Day 73 Patient accepted — Started AD-05 in the companion
Day 78 No meaningful change — Adherence Support AD-05
Day 98 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 98.

Primary contributors, last 14 days

Toxicity-9
Inflammatory activity-8
GI instability-6
Treatment adherence+2

What helped?

Adherence Support AD-05Day 72
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

18.9/100

worsening · +1.6 vs previous 14 d

Toxicity

Blood

9.6/100

worsening · +1.6 vs previous 14 d

Sleep quality

Wearable

67.2/100

stable · -0.0 vs previous 14 d

Energy level

Daily log

5.9/10

worsening · -0.3 vs previous 14 d

Stress level

Daily log

2.8/10

worsening · +0.3 vs previous 14 d

Steps

Wearable

3,813

improving · +155 vs previous 14 d

Adherence

Companion

86.3 %

stable · -3.3 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 69 from the failing basin, 35 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5
Insoluble fibre (supports)
perturbation · steering +3
Adherence Support AD-05
intervention · steering +2.9
Insoluble fibre
supporter · GI -1.8 next day

Main detractors to watch

FUT2 non-secretor
hidden · steering -10.6
Histamine load
perturbation · steering -5.9
Alcohol
perturbation · steering -3.7
Poor-sleep week
perturbation · steering -3
Histamine load
detractor · GI +3.6 next day
Alcohol
detractor · GI +2.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+3.6detractor · 95%
Alcohol
+2.3detractor · 62%
Insoluble fibre
-1.8supporter · 62%
Dietary fat load
+1.7no signal · 42%
Spicy / capsaicin
-0.5no signal · 15%
Simple carbohydrates
-0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Autonomic recovery ↑20
- Wearable3,813 steps/day

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 4.3 · butyrate capacity 48/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 53 ms
Sleep: 8.0 h
Steps: 3,195
Resting HR: 60 bpm

Daily log: GI score 19, nutritional resilience 61, adherence 86.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01483	54%	S14	AD-05	no change	35
P-01377	48%	S11	AD-05	no change	42
P-01679	39%	S12	AD-05	no change	39
P-01804	32%	S19	AD-05	improved	61
P-01848	32%	S05	AD-05	no change	23
P-01773	29%	S05	AD-05	improved	27
P-01313	46%	S01	BR-03	improved	32
P-01350	44%	S19	BR-03	no change	34
P-01689	43%	S13	BR-03	no change	50
P-01450	40%	S09	BR-03	no change	36
P-01468	39%	S06	BR-03	no change	41
P-01329	26%	S08	BR-03	improved	79