Patient P-01554
Synthetic patientNBL-101 · Day 92 · 55–64 · F · baseline S05Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
71%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S05
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 53 GI-04 recommended — GI Support Protocol GI-04
- Day 54 Patient accepted — Started GI-04 in the companion
- Day 62 GI symptom burden −20% vs expected — GI Support Protocol GI-04
- Day 68 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Treatment adherence-14
- GI instability+7
- Inflammatory activity+6
- Nutritional resilience-5
- Toxicity-2
What helped?
- GI Support Protocol GI-04Day 53Result: symptom burden −20%
LIFE OS recommendation
Dietary Support Protocol NP-02
58%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion62.1/100
worsening · +6.4 vs previous 14 d
Toxicity
Blood45.2/100
stable · -1.8 vs previous 14 d
Sleep quality
Wearable36.2/100
stable · -0.1 vs previous 14 d
Energy level
Daily log3.6/10
stable · -0.1 vs previous 14 d
Stress level
Daily log7.5/10
stable · +0.1 vs previous 14 d
Steps
Wearable1,391
worsening · -318 vs previous 14 d
Adherence
Companion46.7 %
worsening · -15.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 26 from the failing basin, 66 from restoration.
Would help
Would not help
- Keep fat lowGI +5 next day on high-intake days · n 23
- Keep simple carbs lowGI +4 next day on high-intake days · n 16
- Keep histamine lowGI +2.9 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5detractor · 95%
- Simple carbohydrates+4detractor · 95%
- Histamine load+2.9detractor · 79%
- Insoluble fibre+2.7detractor · 60%
- Spicy / capsaicin+1.3no signal · 31%
- Alcohol-1no signal · 23%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 62 and rising
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 60
- WearableHRV 32 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 42/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓45
- WearableResting HR 86 bpm
- Wearable1,391 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 45
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 42/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 33 ms
- Sleep
- 6.5 h
- Steps
- 1,618
- Resting HR
- 85 bpm
Daily log: GI score 62, nutritional resilience 38, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01327 | 40% | S01 | GI-04 | improved | 56 |
| P-01813 | 38% | S01 | NP-02 | no change | 40 |
| P-01688 | 37% | S01 | GI-04 | improved | 40 |
| P-01310 | 33% | S01 | — | — | 57 |
| P-01877 | 29% | S01 | CR-01 | improved | 67 |
| P-01821 | 21% | S01 | — | — | 58 |
| P-01823 | 21% | S01 | — | — | 57 |
| P-01604 | 20% | S01 | — | — | 71 |
| P-01452 | 45% | S02 | GI-04 | improved | 46 |
| P-01635 | 37% | S02 | GI-04 | improved | 49 |
| P-01459 | 30% | S02 | — | — | 51 |
| P-01498 | 21% | S02 | — | — | 56 |