Patient P-01555
Synthetic patientNBL-101 · Day 100 · 35–44 · F · baseline S06Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
12%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S06
- Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 14 GI-04 recommended — GI Support Protocol GI-04
- Day 15 Patient accepted — Started GI-04 in the companion
- Day 23 GI symptom burden −20% vs expected — GI Support Protocol GI-04
- Day 29 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 10.
Primary contributors, last 14 days
- Toxicity-7
- Nutritional resilience+4
- GI instability+3
- Treatment adherence-3
- Inflammatory activity-2
What helped?
- GI Support Protocol GI-04Day 14Result: symptom burden −20%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion19.1/100
improving · -10.3 vs previous 14 d
Toxicity
Blood8.8/100
improving · -8.8 vs previous 14 d
Sleep quality
Wearable42.5/100
improving · +5.7 vs previous 14 d
Energy level
Daily log5.7/10
improving · +0.8 vs previous 14 d
Stress level
Daily log2.5/10
improving · -0.9 vs previous 14 d
Steps
Wearable6,098
improving · +595 vs previous 14 d
Adherence
Companion94.9 %
stable · -0.5 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 76 from the failing basin, 22 from restoration.
Good elements to keep
- GI Support Protocol GI-04intervention · steering +30.6
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Simple carbohydratesperturbation · steering -9.1
- Dietary fat loadperturbation · steering -9.1
- Low microbial diversityhidden · steering -7.7
- Simple carbohydratesdetractor · GI +6.2 next day
- Dietary fat loaddetractor · GI +5.2 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+6.2detractor · 95%
- Dietary fat load+5.2detractor · 95%
- Insoluble fibre-1.5no signal · 23%
- Histamine load+1.1no signal · 20%
- Alcohol-1.1no signal · 22%
- Spicy / capsaicin-0.8no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 41/100
- MicrobiomeF. prausnitzii depleted
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Intermediate metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.3 · butyrate capacity 41/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 69 ms
- Sleep
- 6.6 h
- Steps
- 6,498
- Resting HR
- 70 bpm
Daily log: GI score 19, nutritional resilience 70, adherence 95.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.