600 patients66,869 observations120 daysLIVE

Patient P-01560

Synthetic patientNBL-101 · Day 114 · 25–34 · M · baseline S19Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
28%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S19
  2. Day 31 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 31.

Primary contributors, last 14 days
  • Toxicity+14
  • Inflammatory activity+6
  • Nutritional resilience-5
  • Treatment adherence-4
  • GI instability-3

What helped?

No interventions yet.

    LIFE OS recommendation
    Dietary Support Protocol NP-02
    62%
    probability of meaningful tolerance improvement
    • 284 similar trajectories
    • 100% showed improvement
    • median effect visible after 10 days

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    36.7/100
    improving · -2.8 vs previous 14 d
    Toxicity
    Blood
    33.7/100
    worsening · +6.7 vs previous 14 d
    Sleep quality
    Wearable
    61.4/100
    stable · +0.3 vs previous 14 d
    Energy level
    Daily log
    5.8/10
    improving · +0.3 vs previous 14 d
    Stress level
    Daily log
    6.5/10
    worsening · +0.2 vs previous 14 d
    Steps
    Wearable
    7,070
    stable · +239 vs previous 14 d
    Adherence
    Companion
    94.8 %
    worsening · -5.8 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 55 from the failing basin, 32 from restoration.

    Would help
    • NP-02 Dietary Support Protocol
      74% improved among 23 similar · onset 10 d · confidence 50%
    Would not help
    • HY-01 Hydration Protocol
      only 33% improved among 9 similar
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Alcohol
      -1.8no signal · 33%
    • Histamine load
      -1.7no signal · 26%
    • Dietary fat load
      -1no signal · 15%
    • Simple carbohydrates
      -0.9no signal · 15%
    • Spicy / capsaicin
      -0.5no signal · 15%
    • Insoluble fibre
      +0.3no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling 65
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • BloodInflammatory load index 43
      • WearableHRV 25 ms, trending down
    • Mucosal barrier integrity 30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Butyrate / short-chain fatty acid production 25
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery 25
      • WearableResting HR 76 bpm
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 4 · butyrate capacity 72/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    27 ms
    Sleep
    7.6 h
    Steps
    7,072
    Resting HR
    72 bpm
    Daily log: GI score 37, nutritional resilience 50, adherence 95.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0180450%S19AD-05improved61
    P-0154128%S09AD-05no change43
    P-0137727%S11AD-05no change42
    P-0148326%S14AD-05no change35
    P-0167926%S12AD-05no change39
    P-0168929%S13BR-03no change50
    P-0135027%S19BR-03no change34
    P-0132926%S08BR-03improved79
    P-0143039%S05CR-01improved54
    P-0137133%S06CR-01improved63
    P-0144231%S13CR-01improved61
    P-0169630%S20CR-01improved59