Patient P-01562
Synthetic patientNBL-101 · Day 95 · 65–74 · M · baseline S04Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
32%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S04
- Day 13 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 14 HY-01 recommended — Hydration Protocol HY-01
- Day 15 Patient accepted — Started HY-01 in the companion
- Day 19 No meaningful change — Hydration Protocol HY-01
What changed?
Trajectory began diverging from predicted response on Day 13.
Primary contributors, last 14 days
- GI instability+9
- Treatment adherence-8
- Inflammatory activity+4
- Nutritional resilience+3
What helped?
- Hydration Protocol HY-01Day 14Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion29.9/100
worsening · +8.8 vs previous 14 d
Toxicity
Blood19.3/100
stable · -0.1 vs previous 14 d
Sleep quality
Wearable69.4/100
stable · -2.5 vs previous 14 d
Energy level
Daily log5.5/10
worsening · -0.7 vs previous 14 d
Stress level
Daily log3.8/10
worsening · +0.3 vs previous 14 d
Steps
Wearable4,911
worsening · -672 vs previous 14 d
Adherence
Companion88.2 %
worsening · -5.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 60 from the failing basin, 32 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- HY-01 Hydration Protocolalready tried, no meaningful change
- Keep fat lowGI +6.7 next day on high-intake days · n 17
- Keep simple carbs lowGI +6.1 next day on high-intake days · n 18
- Keep histamine lowGI +5.7 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.7detractor · 95%
- Simple carbohydrates+6.1detractor · 95%
- Histamine load+5.7detractor · 95%
- Alcohol+5.1detractor · 95%
- Insoluble fibre-1.7no signal · 22%
- Spicy / capsaicin-0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 23/100
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.2 · butyrate capacity 23/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 58 ms
- Sleep
- 7.7 h
- Steps
- 4,158
- Resting HR
- 60 bpm
Daily log: GI score 30, nutritional resilience 61, adherence 88.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.