600 patients66,869 observations120 daysLIVE

Patient P-01565

Synthetic patientNBL-101 · Day 91 · 45–54 · F · baseline S19Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
29%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S19
  2. Day 10 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days
  • GI instability+9
  • Toxicity-6
  • Inflammatory activity-2
  • Nutritional resilience+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    22.2/100
    worsening · +4.1 vs previous 14 d
    Toxicity
    Blood
    12.5/100
    worsening · +2.7 vs previous 14 d
    Sleep quality
    Wearable
    49.6/100
    worsening · -4.0 vs previous 14 d
    Energy level
    Daily log
    5.1/10
    worsening · -0.8 vs previous 14 d
    Stress level
    Daily log
    3.7/10
    worsening · +0.2 vs previous 14 d
    Steps
    Wearable
    1,763
    worsening · -450 vs previous 14 d
    Adherence
    Companion
    78.7 %
    stable · -0.6 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 62 from the failing basin, 51 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep alcohol low
      GI +4.2 next day on high-intake days · n 18
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Alcohol
      +4.2detractor · 95%
    • Spicy / capsaicin
      +1.6no signal · 38%
    • Simple carbohydrates
      +1.5no signal · 40%
    • Dietary fat load
      -1.2no signal · 25%
    • Histamine load
      +1.1no signal · 27%
    • Insoluble fibre
      +0.8no signal · 19%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling 35
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 35 ms, trending down
    • Butyrate / short-chain fatty acid production 25
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery 20
      • Wearable1,763 steps/day
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Rapid metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 4.4 · butyrate capacity 80/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    33 ms
    Sleep
    7.5 h
    Steps
    3,113
    Resting HR
    60 bpm
    Daily log: GI score 22, nutritional resilience 65, adherence 79.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0147520%S0476
    P-0157720%S20HY-01no change74
    P-0153520%S1972
    P-0181921%S1372
    P-0160422%S0171
    P-0138623%S1370
    P-0145320%S1970
    P-0135222%S2070
    P-0175022%S1669
    P-0135520%S1469
    P-0150822%S1868
    P-0136920%S0868