Patient P-01565

Synthetic patientNBL-101 · Day 91 · 45–54 · F · baseline S19Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

29%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S19
Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days

GI instability+9
Toxicity-6
Inflammatory activity-2
Nutritional resilience+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

22.2/100

worsening · +4.1 vs previous 14 d

Toxicity

Blood

12.5/100

worsening · +2.7 vs previous 14 d

Sleep quality

Wearable

49.6/100

worsening · -4.0 vs previous 14 d

Energy level

Daily log

5.1/10

worsening · -0.8 vs previous 14 d

Stress level

Daily log

3.7/10

worsening · +0.2 vs previous 14 d

Steps

Wearable

1,763

worsening · -450 vs previous 14 d

Adherence

Companion

78.7 %

stable · -0.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 62 from the failing basin, 51 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep alcohol low
GI +4.2 next day on high-intake days · n 18

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+4.2detractor · 95%
Spicy / capsaicin
+1.6no signal · 38%
Simple carbohydrates
+1.5no signal · 40%
Dietary fat load
-1.2no signal · 25%
Histamine load
+1.1no signal · 27%
Insoluble fibre
+0.8no signal · 19%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 35 ms, trending down
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↓20
- Wearable1,763 steps/day

DNA

Fictional pharmacogenomic panel

CYP2D6 Rapid metabolizer
Expected exposure

Microbiome

Shannon diversity 4.4 · butyrate capacity 80/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 33 ms
Sleep: 7.5 h
Steps: 3,113
Resting HR: 60 bpm

Daily log: GI score 22, nutritional resilience 65, adherence 79.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01773	45%	S05	AD-05	improved	27
P-01483	31%	S14	AD-05	no change	35
P-01377	30%	S11	AD-05	no change	42
P-01679	30%	S12	AD-05	no change	39
P-01541	28%	S09	AD-05	no change	43
P-01848	28%	S05	AD-05	no change	23
P-01804	24%	S19	AD-05	improved	61
P-01313	34%	S01	BR-03	improved	32
P-01350	31%	S19	BR-03	no change	34
P-01450	30%	S09	BR-03	no change	36
P-01468	26%	S06	BR-03	no change	41
P-01689	25%	S13	BR-03	no change	50