Patient P-01585
Therapy response
Stable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
19%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S13
- Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 10.
Primary contributors, last 14 days
- Toxicity-7
- Nutritional resilience+5
- Inflammatory activity+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 36 ms, trending down
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 30/100
- MicrobiomeF. prausnitzii depleted
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.7 h, below personal baseline
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.9 · butyrate capacity 30/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 37 ms
- Sleep
- 6.6 h
- Steps
- 6,190
- Resting HR
- 69 bpm
Daily log: GI score 30, nutritional resilience 63, adherence 93.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01342 | 55% | S11 | DT-01 | improved | 48 |
| P-01871 | 50% | S16 | HY-01 | no change | 57 |
| P-01823 | 49% | S01 | — | — | 57 |
| P-01884 | 48% | S19 | GI-04 | no change | 54 |
| P-01346 | 47% | S12 | DT-01 | improved | 52 |
| P-01593 | 47% | S10 | HY-01 | improved | 56 |
| P-01787 | 47% | S19 | — | — | 51 |
| P-01701 | 46% | S11 | — | — | 55 |
| P-01818 | 46% | S15 | — | — | 46 |
| P-01487 | 45% | S03 | — | — | 48 |
| P-01752 | 45% | S20 | DT-01 | improved | 50 |
| P-01392 | 44% | S03 | — | — | 47 |