Patient P-01884
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
53%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S19
- Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 14 GI-04 recommended — GI Support Protocol GI-04
- Day 15 Patient accepted — Started GI-04 in the companion
- Day 23 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 12.
Primary contributors, last 14 days
- GI instability+29
- Inflammatory activity+20
- Nutritional resilience-16
- Treatment adherence+4
- Toxicity-2
What helped?
- GI Support Protocol GI-04Day 14Result: no meaningful change
LIFE OS recommendation
Clinician Review CR-01
72%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 5 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 24 ms, trending down
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓20
- Wearable2,436 steps/day
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.3 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 33 ms
- Sleep
- 6.3 h
- Steps
- 3,490
- Resting HR
- 66 bpm
Daily log: GI score 30, nutritional resilience 57, adherence 97.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01787 | 53% | S19 | — | — | 51 |
| P-01701 | 49% | S11 | — | — | 55 |
| P-01585 | 48% | S13 | — | — | 49 |
| P-01823 | 48% | S01 | — | — | 57 |
| P-01871 | 47% | S16 | HY-01 | no change | 57 |
| P-01342 | 46% | S11 | DT-01 | improved | 48 |
| P-01461 | 44% | S19 | — | — | 61 |
| P-01430 | 43% | S05 | CR-01 | improved | 54 |
| P-01446 | 43% | S03 | — | — | 53 |
| P-01593 | 43% | S10 | HY-01 | improved | 56 |
| P-01631 | 43% | S14 | — | — | 59 |
| P-01804 | 43% | S19 | AD-05 | improved | 61 |