Patient P-01585
Synthetic patientNBL-101 · Day 109 · 35–44 · F · baseline S13Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
19%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S13
- Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 10.
Primary contributors, last 14 days
- Toxicity-7
- Nutritional resilience+5
- Inflammatory activity+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion30.4/100
improving · -3.7 vs previous 14 d
Toxicity
Blood14.5/100
worsening · +2.7 vs previous 14 d
Sleep quality
Wearable25/100
stable · +0.8 vs previous 14 d
Energy level
Daily log4.8/10
stable · -0.2 vs previous 14 d
Stress level
Daily log5/10
improving · -0.3 vs previous 14 d
Steps
Wearable5,548
improving · +831 vs previous 14 d
Adherence
Companion93.2 %
stable · -2.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading drifting · 57 from the failing basin, 34 from restoration.
Good elements to keep
- Stable without identifiable pulls.
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Dietary fat loadperturbation · steering -11.2
- Simple carbohydratesperturbation · steering -8.8
- Spicy / capsaicinperturbation · steering -8.3
- Dietary fat loaddetractor · GI +5.9 next day
- Spicy / capsaicindetractor · GI +4.6 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.9detractor · 95%
- Spicy / capsaicin+4.6detractor · 95%
- Simple carbohydrates+4.5detractor · 95%
- Insoluble fibre+2.2no signal · 41%
- Alcohol+2.1no signal · 35%
- Histamine load-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 36 ms, trending down
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 30/100
- MicrobiomeF. prausnitzii depleted
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.7 h, below personal baseline
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.9 · butyrate capacity 30/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 37 ms
- Sleep
- 6.6 h
- Steps
- 6,190
- Resting HR
- 69 bpm
Daily log: GI score 30, nutritional resilience 63, adherence 93.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01342 | 55% | S11 | DT-01 | improved | 48 |
| P-01346 | 47% | S12 | DT-01 | improved | 52 |
| P-01593 | 47% | S10 | HY-01 | improved | 56 |
| P-01752 | 45% | S20 | DT-01 | improved | 50 |
| P-01571 | 44% | S13 | SC-12 | improved | 57 |
| P-01861 | 43% | S12 | HY-01 | improved | 47 |
| P-01430 | 41% | S05 | CR-01 | improved | 54 |
| P-01804 | 40% | S19 | AD-05 | improved | 61 |
| P-01374 | 39% | S08 | HY-01 | improved | 49 |
| P-01555 | 37% | S06 | GI-04 | improved | 56 |
| P-01455 | 36% | S01 | GI-04 | improved | 61 |
| P-01618 | 34% | S10 | GI-04 | improved | 39 |