Patient P-01593

Synthetic patientNBL-101 · Day 120 · 45–54 · M · baseline S10Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Deteriorating

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Declining

Discontinuation risk

11%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S10
Day 11 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 14 HY-01 recommended — Hydration Protocol HY-01
Day 15 Patient accepted — Started HY-01 in the companion
Day 19 GI symptom burden −22% vs expected — Hydration Protocol HY-01
Day 25 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 11.

Primary contributors, last 14 days

Nutritional resilience-11
Toxicity+5
Inflammatory activity+4

What helped?

Hydration Protocol HY-01Day 14
Result: symptom burden −22%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

17.1/100

stable · -0.2 vs previous 14 d

Toxicity

Blood

14.7/100

stable · +0.5 vs previous 14 d

Sleep quality

Wearable

58.3/100

improving · +3.9 vs previous 14 d

Energy level

Daily log

5.9/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

4.4/10

stable · +0.1 vs previous 14 d

Steps

Wearable

4,786

stable · +106 vs previous 14 d

Adherence

Companion

93.8 %

worsening · -4.8 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 74 from the failing basin, 22 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Keep fat low
GI +4.1 next day on high-intake days · n 16
Keep simple carbs low
GI +4.1 next day on high-intake days · n 20
Keep histamine low
GI +3.7 next day on high-intake days · n 18

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+4.1detractor · 95%
Simple carbohydrates
+4.1detractor · 95%
Histamine load
+3.7detractor · 95%
Alcohol
+1.6no signal · 46%
Insoluble fibre
+0.8no signal · 19%
Spicy / capsaicin
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 34 ms, trending down
Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 44/100

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 2.3 · butyrate capacity 44/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 33 ms
Sleep: 8.0 h
Steps: 4,484
Resting HR: 65 bpm

Daily log: GI score 17, nutritional resilience 63, adherence 94.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01346	55%	S12	DT-01	improved	52
P-01871	52%	S16	HY-01	no change	57
P-01519	50%	S06	—	—	48
P-01596	50%	S08	—	—	51
P-01787	49%	S19	—	—	51
P-01701	48%	S11	—	—	55
P-01487	47%	S03	—	—	48
P-01585	47%	S13	—	—	49
P-01342	46%	S11	DT-01	improved	48
P-01633	46%	S16	GI-04	no change	55
P-01818	46%	S15	—	—	46
P-01434	45%	S18	—	—	53