Patient P-01598
Synthetic patientNBL-101 · Day 109 · 25–34 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Stable
GI state
Unstable
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
75%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 58 GI-04 recommended — GI Support Protocol GI-04
- Day 59 Patient accepted — Started GI-04 in the companion
- Day 67 No meaningful change — GI Support Protocol GI-04
- Day 69 ME-01 recommended — Monitoring Escalation ME-01
- Day 70 Patient accepted — Started ME-01 in the companion
- Day 73 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Nutritional resilience-7
- Treatment adherence+7
- GI instability+3
- Toxicity-2
What helped?
- GI Support Protocol GI-04Day 58Result: no meaningful change
- Monitoring Escalation ME-01Day 69Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
58%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion60.6/100
stable · -0.3 vs previous 14 d
Toxicity
Blood48.7/100
stable · -1.0 vs previous 14 d
Sleep quality
Wearable23/100
improving · +3.1 vs previous 14 d
Energy level
Daily log2.1/10
improving · +0.1 vs previous 14 d
Stress level
Daily log6.5/10
stable · -0.2 vs previous 14 d
Steps
Wearable7,764
stable · +96 vs previous 14 d
Adherence
Companion51.4 %
improving · +2.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 27 from the failing basin, 63 from restoration.
Would help
Would not help
- GI-04 GI Support Protocolalready tried, no meaningful change
- Keep fat lowGI +3.1 next day on high-intake days · n 17
- Keep simple carbs lowGI +2.3 next day on high-intake days · n 19
- Keep fibre lowGI +1.9 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+3.1detractor · 95%
- Simple carbohydrates+2.3detractor · 89%
- Insoluble fibre+1.9detractor · 73%
- Alcohol+1.9detractor · 75%
- Histamine load+0.2no signal · 15%
- Spicy / capsaicin+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 49
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 38/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓45
- WearableResting HR 72 bpm
- WearableShort sleep window
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 61 and rising
- WearableSleep 5.4 h, below personal baseline
- Inflammatory signalling ↑25
- BloodInflammatory load index 55
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 2 · butyrate capacity 38/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 55 ms
- Sleep
- 5.4 h
- Steps
- 7,088
- Resting HR
- 68 bpm
Daily log: GI score 61, nutritional resilience 35, adherence 51.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01328 | 57% | S14 | SC-12 | no change | 49 |
| P-01675 | 57% | S14 | NP-02 | improved | 38 |
| P-01389 | 54% | S14 | SC-12 | improved | 46 |
| P-01494 | 54% | S14 | GI-04 | improved | 42 |
| P-01834 | 54% | S14 | NP-02 | improved | 44 |
| P-01413 | 53% | S14 | GI-04 | improved | 44 |
| P-01845 | 53% | S14 | NP-02 | improved | 47 |
| P-01891 | 53% | S14 | SC-12 | improved | 41 |
| P-01531 | 52% | S14 | ME-01 | improved | 51 |
| P-01412 | 50% | S14 | NP-02 | improved | 49 |
| P-01433 | 50% | S14 | GI-04 | improved | 48 |
| P-01436 | 50% | S14 | GI-04 | improved | 38 |