Patient P-01606
Therapy response
Stable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
77%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S06
- Day 78 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 82 GI-04 recommended — GI Support Protocol GI-04
- Day 83 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 78.
Primary contributors, last 14 days
- Nutritional resilience-12
- Toxicity+10
- GI instability+9
- Inflammatory activity+7
What helped?
- GI Support Protocol GI-04Day 82Declined by patient
LIFE OS recommendation
GI Support Protocol GI-04
67%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion75.3/100
worsening · +6.5 vs previous 14 d
Toxicity
Blood57.9/100
improving · -4.6 vs previous 14 d
Sleep quality
Wearable17.9/100
worsening · -8.4 vs previous 14 d
Energy level
Daily log2.3/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log7.9/10
stable · +0.1 vs previous 14 d
Steps
Wearable3,736
improving · +260 vs previous 14 d
Adherence
Companion69.1 %
worsening · -9.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 37 from the failing basin, 75 from restoration.
Would help
Would not help
- Keep fat lowGI +4.1 next day on high-intake days · n 24
- Keep simple carbs lowGI +2 next day on high-intake days · n 27
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.1detractor · 95%
- Simple carbohydrates+2detractor · 62%
- Insoluble fibre+0.9no signal · 25%
- Histamine load+0.6no signal · 15%
- Spicy / capsaicin+0.6no signal · 16%
- Alcohol+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↓65
- WearableResting HR 75 bpm
- Wearable3,736 steps/day
- WearableShort sleep window
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 27/100
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑55
- DNADPYD *2A → slower clearance
- BloodToxicity index 58
- Inflammatory signalling ↑45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 67
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 75 and rising
- WearableSleep 5.6 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Intermediate metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.8 · butyrate capacity 27/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 51 ms
- Sleep
- 5.5 h
- Steps
- 3,231
- Resting HR
- 75 bpm
Daily log: GI score 75, nutritional resilience 22, adherence 69.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01877 | 40% | S01 | CR-01 | improved | 67 |
| P-01310 | 38% | S01 | — | — | 57 |
| P-01813 | 25% | S01 | NP-02 | no change | 40 |
| P-01327 | 24% | S01 | GI-04 | improved | 56 |
| P-01688 | 24% | S01 | GI-04 | improved | 40 |
| P-01604 | 20% | S01 | — | — | 71 |
| P-01823 | 19% | S01 | — | — | 57 |
| P-01459 | 33% | S02 | — | — | 51 |
| P-01452 | 28% | S02 | GI-04 | improved | 46 |
| P-01635 | 26% | S02 | GI-04 | improved | 49 |
| P-01498 | 20% | S02 | — | — | 56 |
| P-01499 | 19% | S02 | — | — | 65 |