Patient P-01609

Synthetic patientNBL-101 · Day 117 · 55–64 · M · baseline S12Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Favorable

Discontinuation risk

15%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S12
Day 11 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 14 GI-04 recommended — GI Support Protocol GI-04
Day 15 Patient accepted — Started GI-04 in the companion
Day 23 No meaningful change — GI Support Protocol GI-04

What changed?

Trajectory began diverging from predicted response on Day 11.

Primary contributors, last 14 days

GI instability-10
Inflammatory activity-8
Toxicity+8
Treatment adherence+3
Nutritional resilience+2

What helped?

GI Support Protocol GI-04Day 14
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

19.3/100

improving · -6.7 vs previous 14 d

Toxicity

Blood

20.6/100

worsening · +3.4 vs previous 14 d

Sleep quality

Wearable

49.8/100

improving · +3.1 vs previous 14 d

Energy level

Daily log

5.9/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

3/10

improving · -0.2 vs previous 14 d

Steps

Wearable

5,456

improving · +385 vs previous 14 d

Adherence

Companion

91.7 %

stable · +1.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 70 from the failing basin, 30 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

GI-04 GI Support Protocol
already tried, no meaningful change
Keep fat low
GI +4.3 next day on high-intake days · n 19

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+4.3detractor · 95%
Simple carbohydrates
+2.3no signal · 55%
Spicy / capsaicin
-1.5no signal · 34%
Histamine load
-1.1no signal · 19%
Alcohol
-0.6no signal · 15%
Insoluble fibre
-0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↑45
- WearableResting HR 72 bpm
- WearableShort sleep window
Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 30/100
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2 · butyrate capacity 30/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 66 ms
Sleep: 5.9 h
Steps: 5,231
Resting HR: 72 bpm

Daily log: GI score 19, nutritional resilience 61, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01861	61%	S12	HY-01	improved	47
P-01455	47%	S01	GI-04	improved	61
P-01555	47%	S06	GI-04	improved	56
P-01752	47%	S20	DT-01	improved	50
P-01618	46%	S10	GI-04	improved	39
P-01346	44%	S12	DT-01	improved	52
P-01374	44%	S08	HY-01	improved	49
P-01320	43%	S09	HY-01	improved	38
P-01342	42%	S11	DT-01	improved	48
P-01385	41%	S06	HY-01	improved	50
P-01593	39%	S10	HY-01	improved	56
P-01571	38%	S13	SC-12	improved	57