Patient P-01614
Synthetic patientNBL-101 · Day 113 · 25–34 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Deteriorating
Nutritional resilience
Unstable
Discontinuation risk
72%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 GI symptom burden −23% vs expected — Dietary Support Protocol NP-02
- Day 48 Tolerance state changed — Unstable → Improving
- Day 50 GI-04 recommended — GI Support Protocol GI-04
- Day 51 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 51 Patient accepted — Started GI-04 in the companion
- Day 59 GI symptom burden −24% vs expected — GI Support Protocol GI-04
- Day 65 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 51.
Primary contributors, last 14 days
- Nutritional resilience-6
- GI instability+5
- Inflammatory activity+5
- Toxicity+4
What helped?
- Dietary Support Protocol NP-02Day 31Result: symptom burden −23%
- GI Support Protocol GI-04Day 50Result: symptom burden −24%
LIFE OS recommendation
Monitoring Escalation ME-01
87%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion58.3/100
worsening · +7.1 vs previous 14 d
Toxicity
Blood37.3/100
improving · -2.5 vs previous 14 d
Sleep quality
Wearable8.7/100
worsening · -9.3 vs previous 14 d
Energy level
Daily log3.2/10
worsening · -0.6 vs previous 14 d
Stress level
Daily log6.2/10
stable · +0.2 vs previous 14 d
Steps
Wearable6,064
stable · -225 vs previous 14 d
Adherence
Companion53.2 %
worsening · -2.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 35 from the failing basin, 56 from restoration.
Would help
Would not help
- Keep fat lowGI +4.6 next day on high-intake days · n 24
- Keep histamine lowGI +4.6 next day on high-intake days · n 16
- Keep simple carbs lowGI +3.4 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.6detractor · 95%
- Histamine load+4.6detractor · 95%
- Simple carbohydrates+3.4detractor · 95%
- Insoluble fibre+3.1detractor · 91%
- Alcohol-0.3no signal · 15%
- Spicy / capsaicin-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 58 and rising
- WearableSleep 4.8 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 36/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 52
- WearableHRV 25 ms, trending down
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.1 · butyrate capacity 36/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 29 ms
- Sleep
- 5.4 h
- Steps
- 6,622
- Resting HR
- 67 bpm
Daily log: GI score 58, nutritional resilience 41, adherence 53.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01327 | 51% | S01 | GI-04 | improved | 56 |
| P-01688 | 41% | S01 | GI-04 | improved | 40 |
| P-01813 | 36% | S01 | NP-02 | no change | 40 |
| P-01310 | 33% | S01 | — | — | 57 |
| P-01877 | 29% | S01 | CR-01 | improved | 67 |
| P-01604 | 24% | S01 | — | — | 71 |
| P-01821 | 24% | S01 | — | — | 58 |
| P-01823 | 24% | S01 | — | — | 57 |
| P-01635 | 43% | S02 | GI-04 | improved | 49 |
| P-01452 | 36% | S02 | GI-04 | improved | 46 |
| P-01459 | 32% | S02 | — | — | 51 |
| P-01499 | 24% | S02 | — | — | 65 |