Patient P-01624
Synthetic patientNBL-101 · Day 115 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Stable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
61%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 42 GI symptom burden −11% vs expected — Dietary Support Protocol NP-02
- Day 48 Tolerance state changed — Unstable → Improving
- Day 58 ME-01 recommended — Monitoring Escalation ME-01
- Day 59 GI-04 recommended — GI Support Protocol GI-04
- Day 59 Patient accepted — Started ME-01 in the companion
- Day 60 Patient accepted — Started GI-04 in the companion
- Day 62 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
- Day 68 GI symptom burden −24% vs expected — GI Support Protocol GI-04
- Day 74 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 42.
Primary contributors, last 14 days
- Nutritional resilience-10
- Inflammatory activity-7
- Treatment adherence-2
- Toxicity-2
What helped?
- Dietary Support Protocol NP-02Day 31Result: symptom burden −11%
- Monitoring Escalation ME-01Day 58Result: deterioration detected before clinical escalation
- GI Support Protocol GI-04Day 59Result: symptom burden −24%
LIFE OS recommendation
Supportive Compound SC-12
62%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 81% showed improvement
- median effect visible after 6 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion43.3/100
improving · -9.4 vs previous 14 d
Toxicity
Blood44.1/100
worsening · +2.3 vs previous 14 d
Sleep quality
Wearable42.9/100
improving · +3.9 vs previous 14 d
Energy level
Daily log4.7/10
improving · +0.3 vs previous 14 d
Stress level
Daily log6.4/10
improving · -0.4 vs previous 14 d
Steps
Wearable2,574
worsening · -140 vs previous 14 d
Adherence
Companion50.4 %
stable · -0.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 43 from the failing basin, 44 from restoration.
Would help
Would not help
- Keep fat lowGI +4.2 next day on high-intake days · n 20
- Keep simple carbs lowGI +3.3 next day on high-intake days · n 20
- Keep spicy lowGI +2.7 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.2detractor · 95%
- Simple carbohydrates+3.3detractor · 95%
- Spicy / capsaicin+2.7detractor · 84%
- Insoluble fibre+2.4detractor · 70%
- Alcohol+0.6no signal · 15%
- Histamine load-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 47
- WearableHRV 23 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 35/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 44
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Autonomic recovery ↓20
- Wearable2,574 steps/day
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 1.8 · butyrate capacity 35/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 23 ms
- Sleep
- 7.2 h
- Steps
- 2,293
- Resting HR
- 65 bpm
Daily log: GI score 43, nutritional resilience 40, adherence 50.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01327 | 46% | S01 | GI-04 | improved | 56 |
| P-01688 | 43% | S01 | GI-04 | improved | 40 |
| P-01813 | 36% | S01 | NP-02 | no change | 40 |
| P-01310 | 35% | S01 | — | — | 57 |
| P-01877 | 29% | S01 | CR-01 | improved | 67 |
| P-01604 | 24% | S01 | — | — | 71 |
| P-01821 | 24% | S01 | — | — | 58 |
| P-01823 | 24% | S01 | — | — | 57 |
| P-01635 | 48% | S02 | GI-04 | improved | 49 |
| P-01452 | 37% | S02 | GI-04 | improved | 46 |
| P-01459 | 32% | S02 | — | — | 51 |
| P-01499 | 24% | S02 | — | — | 65 |