Patient P-01633
Synthetic patientNBL-101 · Day 110 · 25–34 · F · baseline S16Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
12%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S16
- Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 14 GI-04 recommended — GI Support Protocol GI-04
- Day 15 Patient accepted — Started GI-04 in the companion
- Day 23 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 10.
Primary contributors, last 14 days
- Nutritional resilience+11
- GI instability-7
- Inflammatory activity-6
What helped?
- GI Support Protocol GI-04Day 14Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion16/100
worsening · +0.9 vs previous 14 d
Toxicity
Blood22.4/100
stable · -0.7 vs previous 14 d
Sleep quality
Wearable25/100
improving · +1.7 vs previous 14 d
Energy level
Daily log5.6/10
stable · -0.1 vs previous 14 d
Stress level
Daily log3.3/10
worsening · +0.2 vs previous 14 d
Steps
Wearable9,476
worsening · -412 vs previous 14 d
Adherence
Companion96.3 %
stable · +2.5 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 73 from the failing basin, 23 from restoration.
Good elements to keep
- GI Support Protocol GI-04intervention · steering +11.1
- Daily walks resumedperturbation · steering +3.3
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Low microbial diversityhidden · steering -7.7
- Enterobacteriaceae elevatedhidden · steering -7.4
- Antibiotic courseperturbation · steering -4.7
- Simple carbohydratesdetractor · GI +3.1 next day
- Dietary fat loaddetractor · GI +2.6 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+3.1detractor · 93%
- Dietary fat load+2.6detractor · 84%
- Insoluble fibre+1.9detractor · 63%
- Histamine load-1.6no signal · 51%
- Spicy / capsaicin-1no signal · 31%
- Alcohol-0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 30/100
- MicrobiomeF. prausnitzii depleted
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.3 h, below personal baseline
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.9 · butyrate capacity 30/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 49 ms
- Sleep
- 6.3 h
- Steps
- 9,000
- Resting HR
- 62 bpm
Daily log: GI score 16, nutritional resilience 69, adherence 96.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.