Patient P-01636

Synthetic patientNBL-101 · Day 92 · 55–64 · M · baseline S18Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Deteriorating

GI state

Deteriorating

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

23%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S18
Day 23 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 23.

Primary contributors, last 14 days

Toxicity+6
GI instability+5
Inflammatory activity+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

16.4/100

worsening · +1.2 vs previous 14 d

Toxicity

Blood

22.4/100

stable · -0.4 vs previous 14 d

Sleep quality

Wearable

47.2/100

stable · -1.7 vs previous 14 d

Energy level

Daily log

6.1/10

stable · -0.2 vs previous 14 d

Stress level

Daily log

3.8/10

stable · +0.1 vs previous 14 d

Steps

Wearable

4,020

stable · -164 vs previous 14 d

Adherence

Companion

83.9 %

stable · +2.5 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 67 from the failing basin, 48 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Nothing clearly counter-productive in the record.

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Insoluble fibre
-1.4no signal · 39%
Simple carbohydrates
+0.9no signal · 27%
Dietary fat load
+0.8no signal · 21%
Histamine load
+0.2no signal · 15%
Spicy / capsaicin
+0.1no signal · 15%
Alcohol
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.5 · butyrate capacity 76/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 49 ms
Sleep: 7.4 h
Steps: 5,035
Resting HR: 64 bpm

Daily log: GI score 16, nutritional resilience 65, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01773	48%	S05	AD-05	improved	27
P-01377	32%	S11	AD-05	no change	42
P-01483	32%	S14	AD-05	no change	35
P-01679	32%	S12	AD-05	no change	39
P-01848	30%	S05	AD-05	no change	23
P-01541	29%	S09	AD-05	no change	43
P-01804	25%	S19	AD-05	improved	61
P-01313	35%	S01	BR-03	improved	32
P-01450	34%	S09	BR-03	no change	36
P-01350	31%	S19	BR-03	no change	34
P-01468	29%	S06	BR-03	no change	41
P-01689	26%	S13	BR-03	no change	50