Patient P-01657

Synthetic patientNBL-101 · Day 115 · 55–64 · F · baseline S14Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Deteriorating

GI state

Favorable

Inflammatory state

Stable

Nutritional resilience

Declining

Discontinuation risk

60%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S14
Day 31 NP-02 recommended — Dietary Support Protocol NP-02
Day 32 Patient accepted — Started NP-02 in the companion
Day 42 GI symptom burden −14% vs expected — Dietary Support Protocol NP-02
Day 48 Tolerance state changed — Unstable → Improving
Day 50 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 52 GI-04 recommended — GI Support Protocol GI-04
Day 53 Patient accepted — Started GI-04 in the companion
Day 61 GI symptom burden −38% vs expected — GI Support Protocol GI-04
Day 67 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 50.

Primary contributors, last 14 days

Toxicity+14
Treatment adherence-7
Nutritional resilience-6

What helped?

Dietary Support Protocol NP-02Day 31
Result: symptom burden −14%
GI Support Protocol GI-04Day 52
Result: symptom burden −38%

LIFE OS recommendation

Supportive Compound SC-12

65%

probability of meaningful tolerance improvement

284 similar trajectories
81% showed improvement
median effect visible after 6 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

37.9/100

worsening · +3.1 vs previous 14 d

Toxicity

Blood

46.8/100

worsening · +4.8 vs previous 14 d

Sleep quality

Wearable

36.4/100

worsening · -2.5 vs previous 14 d

Energy level

Daily log

4.4/10

worsening · -0.3 vs previous 14 d

Stress level

Daily log

5.1/10

worsening · +0.4 vs previous 14 d

Steps

Wearable

3,120

stable · -112 vs previous 14 d

Adherence

Companion

46.6 %

worsening · -9.0 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 55 from the failing basin, 33 from restoration.

Would help

ME-01 Monitoring Escalation
100% improved among 72 similar · onset 3 d · confidence 66%
SC-12 Supportive Compound
76% improved among 51 similar · onset 6 d · confidence 66%
CR-01 Clinician Review
100% improved among 7 similar · onset 5 d · confidence 66%

Would not help

Keep fat low
GI +3 next day on high-intake days · n 15
Keep simple carbs low
GI +2.5 next day on high-intake days · n 17
Keep fibre low
GI +2 next day on high-intake days · n 19

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+3detractor · 95%
Simple carbohydrates
+2.5detractor · 87%
Insoluble fibre
+2detractor · 82%
Alcohol
+0.6no signal · 21%
Spicy / capsaicin
+0.6no signal · 18%
Histamine load
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↑65
- WearableResting HR 73 bpm
- Wearable3,120 steps/day
- WearableShort sleep window
Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 34/100
- Daily logFibre intake low in recent food logs
Inflammatory signalling ↓45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 43
Drug metabolism and exposure ↑20
- BloodToxicity index 47
Mucosal barrier integrity ↓10
- WearableSleep 5.7 h, below personal baseline

DNA

Fictional pharmacogenomic panel

CYP2D6 Rapid metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.8 · butyrate capacity 34/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 54 ms
Sleep: 5.7 h
Steps: 3,722
Resting HR: 72 bpm

Daily log: GI score 38, nutritional resilience 50, adherence 47.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01377	25%	S11	AD-05	no change	42
P-01483	24%	S14	AD-05	no change	35
P-01689	25%	S13	BR-03	no change	50
P-01371	33%	S06	CR-01	improved	63
P-01696	30%	S20	CR-01	improved	59
P-01708	30%	S07	CR-01	improved	59
P-01442	28%	S13	CR-01	improved	61
P-01388	27%	S17	CR-01	improved	59
P-01430	26%	S05	CR-01	improved	54
P-01835	25%	S17	CR-01	improved	56
P-01767	25%	S14	DT-01	no change	63
P-01342	24%	S11	DT-01	improved	48