Patient P-01677
Synthetic patientNBL-101 · Day 116 · 65–74 · M · baseline S05Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
21%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S05
- Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 92 BR-03 recommended — Behavioural Recommendation BR-03
- Day 93 Patient accepted — Started BR-03 in the companion
- Day 100 No meaningful change — Behavioural Recommendation BR-03
What changed?
Trajectory began diverging from predicted response on Day 15.
Primary contributors, last 14 days
- GI instability+11
- Inflammatory activity+9
- Treatment adherence-7
- Nutritional resilience-5
What helped?
- Behavioural Recommendation BR-03Day 92Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion14.6/100
worsening · +0.7 vs previous 14 d
Toxicity
Blood10.4/100
improving · -1.3 vs previous 14 d
Sleep quality
Wearable62.9/100
stable · +0.5 vs previous 14 d
Energy level
Daily log6.5/10
stable · +0.0 vs previous 14 d
Stress level
Daily log4/10
stable · -0.1 vs previous 14 d
Steps
Wearable7,285
stable · +260 vs previous 14 d
Adherence
Companion92.7 %
stable · -2.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 94 from the failing basin, 9 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- BR-03 Behavioural Recommendationalready tried, no meaningful change
- Keep histamine lowGI +3.7 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+3.7detractor · 87%
- Spicy / capsaicin+1no signal · 21%
- Dietary fat load+0.9no signal · 16%
- Alcohol+0.8no signal · 15%
- Simple carbohydrates-0.7no signal · 15%
- Insoluble fibre+0.6no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.8 · butyrate capacity 80/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 59 ms
- Sleep
- 7.6 h
- Steps
- 7,824
- Resting HR
- 56 bpm
Daily log: GI score 15, nutritional resilience 66, adherence 93.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.