Patient P-01679

Synthetic patientNBL-101 · Day 113 · 35–44 · F · baseline S12Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Deteriorating

Nutritional resilience

Improving

Discontinuation risk

22%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S12
Day 72 AD-05 recommended — Adherence Support AD-05
Day 73 Patient accepted — Started AD-05 in the companion
Day 78 No meaningful change — Adherence Support AD-05
Day 86 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 86.

Primary contributors, last 14 days

Inflammatory activity+9
Treatment adherence-7
GI instability-4
Nutritional resilience+4

What helped?

Adherence Support AD-05Day 72
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

20/100

worsening · +2.8 vs previous 14 d

Toxicity

Blood

27.1/100

worsening · +2.7 vs previous 14 d

Sleep quality

Wearable

44.7/100

stable · +0.6 vs previous 14 d

Energy level

Daily log

5.7/10

worsening · -0.3 vs previous 14 d

Stress level

Daily log

3.7/10

worsening · +0.3 vs previous 14 d

Steps

Wearable

9,855

stable · -257 vs previous 14 d

Adherence

Companion

77.8 %

stable · -3.0 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 61 from the failing basin, 41 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

AD-05 Adherence Support
already tried, no meaningful change
Keep alcohol low
GI +4.1 next day on high-intake days · n 20
Keep spicy low
GI +2.8 next day on high-intake days · n 21

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+4.1detractor · 95%
Spicy / capsaicin
+2.8detractor · 88%
Insoluble fibre
-0.7no signal · 15%
Histamine load
-0.3no signal · 15%
Dietary fat load
-0.1no signal · 15%
Simple carbohydrates
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone
Autonomic recovery ↓20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Rapid metabolizer
Expected exposure

Microbiome

Shannon diversity 3.4 · butyrate capacity 47/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 57 ms
Sleep: 6.5 h
Steps: 9,123
Resting HR: 58 bpm

Daily log: GI score 20, nutritional resilience 65, adherence 78.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01350	49%	S19	BR-03	no change	34
P-01345	46%	S12	—	—	30
P-01722	46%	S09	—	—	36
P-01846	45%	S01	—	—	37
P-01377	43%	S11	AD-05	no change	42
P-01483	42%	S14	AD-05	no change	35
P-01848	41%	S05	AD-05	no change	23
P-01816	40%	S01	—	—	35
P-01829	40%	S11	—	—	31
P-01882	40%	S18	—	—	44
P-01370	39%	S03	—	—	44
P-01401	39%	S15	—	—	34