Patient P-01689
Synthetic patientNBL-101 · Day 105 · 25–34 · F · baseline S13Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Stable
Discontinuation risk
33%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S13
- Day 72 BR-03 recommended — Behavioural Recommendation BR-03
- Day 73 Patient accepted — Started BR-03 in the companion
- Day 80 No meaningful change — Behavioural Recommendation BR-03
- Day 84 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 84.
Primary contributors, last 14 days
- Toxicity+11
- GI instability+8
- Inflammatory activity+7
- Treatment adherence-3
What helped?
- Behavioural Recommendation BR-03Day 72Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion31/100
worsening · +8.9 vs previous 14 d
Toxicity
Blood24.6/100
worsening · +1.2 vs previous 14 d
Sleep quality
Wearable45.3/100
worsening · -6.6 vs previous 14 d
Energy level
Daily log4.7/10
worsening · -0.8 vs previous 14 d
Stress level
Daily log4.2/10
worsening · +0.7 vs previous 14 d
Steps
Wearable3,369
worsening · -604 vs previous 14 d
Adherence
Companion88 %
worsening · -5.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 57 from the failing basin, 33 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- BR-03 Behavioural Recommendationalready tried, no meaningful change
- Keep histamine lowGI +5.9 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+5.9detractor · 95%
- Insoluble fibre-2.2no signal · 51%
- Spicy / capsaicin-2.1no signal · 42%
- Simple carbohydrates-1.6no signal · 31%
- Dietary fat load+1no signal · 22%
- Alcohol-0.6no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↑40
- Wearable3,369 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 61/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 67 ms
- Sleep
- 6.8 h
- Steps
- 3,940
- Resting HR
- 58 bpm
Daily log: GI score 31, nutritional resilience 59, adherence 88.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.