Patient P-01708
Synthetic patientNBL-101 · Day 116 · 35–44 · F · baseline S07Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
54%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S07
- Day 77 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 82 CR-01 recommended — Clinician Review CR-01
- Day 83 Patient accepted — Started CR-01 in the companion
- Day 88 Deterioration detected before clinical escalation — Clinician Review CR-01
What changed?
Trajectory began diverging from predicted response on Day 77.
Primary contributors, last 14 days
- Toxicity+7
- Treatment adherence+5
- GI instability-4
- Inflammatory activity+3
What helped?
- Clinician Review CR-01Day 82Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
63%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 84% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion57.4/100
improving · -11.3 vs previous 14 d
Toxicity
Blood50.7/100
worsening · +4.7 vs previous 14 d
Sleep quality
Wearable57.1/100
improving · +9.8 vs previous 14 d
Energy level
Daily log3.2/10
improving · +0.7 vs previous 14 d
Stress level
Daily log7.2/10
improving · -0.3 vs previous 14 d
Steps
Wearable487
improving · +232 vs previous 14 d
Adherence
Companion69.8 %
stable · +0.2 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 39 from the failing basin, 54 from restoration.
Would help
Would not help
- Keep simple carbs lowGI +5.5 next day on high-intake days · n 22
- Keep histamine lowGI +5.3 next day on high-intake days · n 20
- Keep fat lowGI +5.1 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+5.5detractor · 95%
- Histamine load+5.3detractor · 95%
- Dietary fat load+5.1detractor · 95%
- Alcohol+0.3no signal · 15%
- Insoluble fibre+0.2no signal · 15%
- Spicy / capsaicin+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 57 and rising
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 25/100
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 54
- Autonomic recovery ↓45
- WearableResting HR 83 bpm
- Wearable487 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 51
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 25/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 52 ms
- Sleep
- 6.9 h
- Steps
- 1,030
- Resting HR
- 82 bpm
Daily log: GI score 57, nutritional resilience 38, adherence 70.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01371 | 40% | S06 | CR-01 | improved | 63 |
| P-01835 | 37% | S17 | CR-01 | improved | 56 |
| P-01877 | 37% | S01 | CR-01 | improved | 67 |
| P-01388 | 36% | S17 | CR-01 | improved | 59 |
| P-01696 | 34% | S20 | CR-01 | improved | 59 |
| P-01442 | 31% | S13 | CR-01 | improved | 61 |
| P-01430 | 23% | S05 | CR-01 | improved | 54 |
| P-01767 | 23% | S14 | DT-01 | no change | 63 |
| P-01342 | 22% | S11 | DT-01 | improved | 48 |
| P-01725 | 43% | S18 | GI-04 | no change | 56 |
| P-01699 | 41% | S04 | GI-04 | improved | 69 |
| P-01438 | 37% | S14 | GI-04 | improved | 56 |