Patient P-01717

Synthetic patientNBL-101 · Day 99 · 45–54 · M · baseline S18Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Improving

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S18

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

GI instability-21
Inflammatory activity-18
Nutritional resilience+17
Toxicity-10
Treatment adherence+3

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

0.7/100

improving · -1.2 vs previous 14 d

Toxicity

Blood

9.9/100

improving · -5.4 vs previous 14 d

Sleep quality

Wearable

74/100

stable · +1.4 vs previous 14 d

Energy level

Daily log

7.7/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

2.2/10

improving · -0.4 vs previous 14 d

Steps

Wearable

7,144

stable · +130 vs previous 14 d

Adherence

Companion

91.7 %

stable · +1.1 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 104 from the failing basin, 22 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5

Main detractors to watch

Histamine load
perturbation · steering -13.5
FUT2 non-secretor
hidden · steering -10.6
Bacteroides fragilis elevated
hidden · steering -7.4
Antibiotic course
perturbation · steering -4.7
Histamine load
detractor · GI +7.5 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+7.5detractor · 95%
Insoluble fibre
-1.4no signal · 21%
Dietary fat load
-0.8no signal · 15%
Alcohol
+0.5no signal · 15%
Simple carbohydrates
+0.1no signal · 15%
Spicy / capsaicin
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.9 · butyrate capacity 67/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 61 ms
Sleep: 7.4 h
Steps: 5,880
Resting HR: 62 bpm

Daily log: GI score 1, nutritional resilience 78, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01766	39%	S05	AD-05	no change	90
P-01541	26%	S09	AD-05	no change	43
P-01804	26%	S19	AD-05	improved	61
P-01377	25%	S11	AD-05	no change	42
P-01329	39%	S08	BR-03	improved	79
P-01677	38%	S05	BR-03	no change	86
P-01495	35%	S07	BR-03	improved	85
P-01468	25%	S06	BR-03	no change	41
P-01689	25%	S13	BR-03	no change	50
P-01654	38%	S08	CR-01	improved	85
P-01430	25%	S05	CR-01	improved	54
P-01479	37%	S15	DT-01	improved	84