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Patient P-01719

Synthetic patientNBL-101 · Day 112 · 55–64 · M · baseline S11Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
31%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S11
  2. Day 81 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 81.

Primary contributors, last 14 days
  • GI instability+11
  • Toxicity+11
  • Inflammatory activity+7
  • Treatment adherence-7
  • Nutritional resilience-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    17.4/100
    stable · +0.1 vs previous 14 d
    Toxicity
    Blood
    18.1/100
    worsening · +2.1 vs previous 14 d
    Sleep quality
    Wearable
    67.1/100
    improving · +2.3 vs previous 14 d
    Energy level
    Daily log
    6.4/10
    stable · -0.0 vs previous 14 d
    Stress level
    Daily log
    4/10
    stable · +0.1 vs previous 14 d
    Steps
    Wearable
    5,513
    worsening · -311 vs previous 14 d
    Adherence
    Companion
    77.3 %
    worsening · -11.4 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 71 from the failing basin, 37 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Nothing clearly counter-productive in the record.
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      -1.3no signal · 26%
    • Dietary fat load
      -1.1no signal · 21%
    • Alcohol
      +0.6no signal · 15%
    • Insoluble fibre
      +0.4no signal · 15%
    • Simple carbohydrates
      +0.3no signal · 15%
    • Spicy / capsaicin
      +0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.8 · butyrate capacity 55/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    62 ms
    Sleep
    7.3 h
    Steps
    5,059
    Resting HR
    63 bpm
    Daily log: GI score 17, nutritional resilience 68, adherence 77.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0137753%S11AD-05no change42
    P-0148346%S14AD-05no change35
    P-0131345%S01BR-03improved32
    P-0137044%S03——44
    P-0141544%S12——32
    P-0145044%S09BR-03no change36
    P-0140143%S15——34
    P-0182943%S11——31
    P-0184643%S01——37
    P-0184743%S01——37
    P-0172242%S09——36
    P-0181642%S01——35